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metronidazole or panic attacks??

by MayMayMeemers, Nov 10, 2009 04:56PM
ok, so i took metronidazole singe dose of 4 pills like advised. it was a 2000 MG script so I can get rid of Trich. I took it at 6pm lastnight

I had panic attacks thinking of the side effects

well at 12am, 6 hours after taking it I was vomiting because my stomach hurt. it stopped and I just have slight upset stomach

today I had really bad headaches, dark urine, mettalic taste in mouth, loss of hunger


idk if this is a symptom of if it panic attacks:

tingling hands, racing heart, heart palps...I got it again when I thought about the really bad side effects!!

now to calm me down can someone answer this SINGLE question



If you were to get severe side effects off metronidazole would it happen sooner or later? hours or days??

cause it said seizers and convolsions

and over dose is vomiting, convolsions

havent had those but if I were to get them off the dose how long and another thing...how long after a dose does the effects leave????

PLEASE HELP!!!!!!!


I feel kinda calm right now and the tingling went away and racing heart but I feel like I have palps and when I turn my eyes I see sparks of light?

is this hypervenalation??????


if I overdosed would I know right away?????? has anyone taken this before cause to be honest...I hate it!!! and think I feel sicker than a dog!!!
Member Comments (17)

by M4Y0U, Nov 10, 2009 06:42PM
To: MayMayMeemers
Hey there,

If you are taking Metronidazole i guess you are having an infection?

In fact yes this med can cause several side effects. Common adverse drug reactions associated with systemic metronidazole therapy include: nausea, diarrhea, and/or metallic taste in the mouth.

Mix that with anxiety and a panic attack and you have the situation you have just described .

Maybe, and i doubt it, you had an overdose but  Metronidazole does not seem to be especially toxic in the case of an overdose. So i don't think it's something to worry about too much especially if the symptoms are gone now.

Metronidazole have a strong interaction with alcohol and can also have produced the vomiting.

Sparks of light again are assosieted with anxiety.

Anyway please note that i'm not a doctor and if you have any concern call you doctor.

Best regards,
M4

by MayMayMeemers, Nov 10, 2009 08:39PM
To: M4Y0U
I feel like ****, my heart keeps racing wildly and it feels like it is palping or double beating. I felt this all day off and on and it doesnt race when I am sitting only when I am walking

Havent had any booze, I don't drink.


this is what I have


Appetite loss; metallic taste; nausea; stomach upset and had  vomiting


but my heart is beating very fast and I am getting scared!!!

doesnt say anything about that as a symptom so is it panic attacks???

by M4Y0U, Nov 10, 2009 10:54PM
To: MayMayMeemers
Metallic taste and nausea are associated with Metronidazole even vomiting but i think it's a mix a both your reaction to the drug and panic attack. Fast heart beating is not associated with Metronidazole. One thing you must consider is you are maybe overeacting to Metronidazole so i suggest you talk to your doctor but i would say it's a panic attack and not an overdose even tho the vomiting is suspect.

Talk about this to your doctor please.

by RCA759I, Nov 11, 2009 12:00AM
To: MayMayMeemers
"ok, so i took metronidazole singe dose of 4 pills like advised. it was a 2000 MG script so I can get rid of Trich. I took it at 6pm lastnight"

^quote

For the treatment of Trichomoniasis, there are two schedules in which Flagyl (Metronidazole) may be utilized. A one-day course of 2 grams, or a seven day course of 250 milligrams, three times daily. The latter is generally more tolerable in terms of adverse side effects. In addition, the seven day option is associated with higher cure rates. The loading dose option (which is what you were given) is fairly high, and it would not be unusual to experience adverse effects. The most common effects (affecting 12%) are: Headache, loss of appetite, nausea/vomiting, GI distress, abdominal cramps and a sharp metallic taste. All of these will dissipate.

Darkened urine affects 1 in 100,000 folks. This is no cause for alarm, and the pigment is associated with a metabolite of Flagyl. This will dissipate in short order.

You asked:

"If you were to get severe side effects off metronidazole would it happen sooner or later? hours or days??"

Severe side effects would manifest rapidly. The drug peaks within two hours, and carries an 8 hour half-life. The symptoms would manifest after the drug has reached its peak plasma level (after a span of two hours). Given the short half-life, symptoms would dissipate within a day or two, once the drug has been eliminated.

You had a combination of typical side effects from the drug, in addition to an anticipatory response which provoked a panic reaction (having read the monograph accompanied with the prescription). There is no concern here.

-Ryan


by MayMayMeemers, Nov 11, 2009 12:16AM
To: RCA759I
So the side effects should go away after two day????

it has been a day since I took it cause I took it monday night and it is past 6pm so that is the first day or second day??

and my rapid heart beat is panic attacks???

I cant die from this right??

by RCA759I, Nov 11, 2009 02:25AM
To: MayMayMeemers
Revision:

I now see that you took the entire 2,000 milligrams in ONE dose. It is actually meant to be taken as 1,000 milligrams, twice daily - not in a single massive dosage. No wonder why it made you ill. Whatever doctor advised you to take the entire amount in one dose is a moron.

Nothing changes, however, and there will be no lasting effects. The drug carries an eight hour elimination half-life, and would follow this course:

-Monday, 6 PM (initial 2,000 mg dose)
-Tuesday, 2 AM (1,000 mg remaining)
-Tuesday, 10 AM (500 mg remaining)
-Tuesday, 6 PM (250 mg remaining)
-Wednesday, 2 AM (125 mg remaining)
-Wednesday, 10 AM (62.5 mg remaining)
-Wednesday, 6 PM (31.25 mg remaining
-Thursday, 2 AM (15.63 mg remaining)
-Thursday, 10 AM (7.81 mg remaining)
-Thursday, 6 PM (3.90 mg remaining)

For all practical purposes, the drug will be eliminated at the 31.25 mg mark, or today at 6 PM. Once it is eliminated, any symptoms that were attributable to it will vanish. There will be no lasting effects, and there is no cause for concern.

Should you ever require treatment again with Flagyl, I would suggest that you divide the total dosage into two equal, 1,000 mg doses, separated by 12 hours. This will minimize the side effects.

As for the rapid pulse, tingling sensations, etc, those were largely induced by an anticipatory response that you developed after reading the pharmacy monograph. So yes, you had a panic reaction. It didn't help that you also had side effects from the drug, but please understand that those side effects are extremely common, affecting 12% of those who take Flagyl.

-Ryan

by MayMayMeemers, Nov 11, 2009 02:35AM
To: RCA759I
OMG! so I could have or did overdose on this?!?!

both pharmacy AND er dr's said 4 pills ALL at once in a single dose. It says so one the bottle, doesnt say anything about 2 doses every 12 hours

says: Take 2000 MG (4 tablets) by mouth  at once for a one time dose.


ugh......My boyfriend is fine however. =/ I wantd to take 2 one day and two the next day but he said no, it has to be taken all at once like what it says.

Should I go to the er???? what if I have an over dose!!!

Panicing again!!

by MayMayMeemers, Nov 11, 2009 02:44AM
I have an std called Trich

treatment of trichomoniasis, a single dose of 2,000 mg may be used after a meal. Various other doses exist according to the infection being treated.

I was listening to the dr and what he told me, take ALL the MG at once

He said not to devide it so did the pharmasist who I got the meds from.


I am shaking now and terrified!!!

by RCA759I, Nov 11, 2009 02:51AM
To: MayMayMeemers
NO, you did not overdose! It CAN be taken as a single dose, but it is rarely prescribed that way for Trich. The dosage is usually divided, and taken 12 hours apart to minimize side effects.

The drug itself is used well in excess of 2,000 mgs to treat other types of infection (ie: c-diff), so no worries.

Frankly, it would be pretty hard to "overdose" on this drug. Believe me, you are fine.

by RCA759I, Nov 11, 2009 02:58AM
To: MayMayMeemers
Again, let me reiterate that it CAN be taken as a single dose, or in two divided doses. Obviously, if you take it in two divided doses, the side effect profile diminishes somewhat. It is more frequently prescribed this way for that reason.

The official prescribing information (PDR 2009):

Trichomoniasis:

In the Female:

One-day treatment—two grams of Flagyl, given either as a single dose or in two divided
doses of one gram each given in the same day.

Seven-day course of treatment—250 mg three times daily for seven consecutive days.
There is some indication from controlled comparative studies that cure rates as
determined by vaginal smears, signs and symptoms, may be higher after a seven-day
course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure
compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may
minimize reinfection by protecting the patient long enough for the sexual contacts to
obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

by MayMayMeemers, Nov 11, 2009 03:04AM
Ok, Yeah, he was gonna do a 7 day treatment but changed his mind and gave me and my boyfriend both 4 500MG pills to take at once. Maybe he thought it would clear it up faster? not sure but the pharmasist said the same thing...take it all at once and dont drink 48 hours after taking it which we havent had anything. All the sites I have been too..which are millions they all say one high dose. >.< UGH!!!! so does this mean I have until thursday for it to be out of my system??

by RCA759I, Nov 11, 2009 03:21AM
To: MayMayMeemers
It will be out of your system this evening (for all practical purposes). Anything below 60 milligrams is trivial. So, 6 PM this evening - 48 hours following your first dose.

The reason why the pharmacist suggested not to drink for 48 hours is outlined above in my table. That is how long the drug takes to clear your system. If mixed with alcohol, it acts similarly to Antabuse, and produces flushing, nausea and other nasty effects.

Trich doesn't clear up faster with one large dose. Dividing the dose produces the same effect. The seven day course is the most effective, however, the one time dose is usually sufficient.

Hang in there, and don't let this consume you. There is nothing to worry about!

Ryan

by MayMayMeemers, Nov 11, 2009 04:29AM
To: RCA759I
I just vomited again at 1:30am

that is twice now... 12am tuesday and 1:30am today is this a side effect that is normal?? I also have a horrid headache right now...Heart was racing again, thought about having an overdose... >.Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with Metronidazole. Because a side effect is stated here, it does not mean that all people using Metronidazole will experience that or any side effect.
I put an X on the side effects I have:

- Confusion;
X- Darkening of the urine;
- Decrease in the number of white blood cells in the blood (leucopenia);
- Disorder of the peripheral nerves called peripheral neuropathy that causes weakness and numbness (on prolonged or intensive therapy);
- Disturbances of the gut such as diarrhoea constipation nausea vomiting or abdominal pain;
- Dizziness;
- Drowsiness;
X- Headache;
- Inflamed and sore mouth;
- Itchy rash (urticaria);
- Liver disorders;
X- Loss of appetite;
- Pain in the muscles or joints;
- Seizures;
X- Sensation of a furry tongue;
- Severe swelling of lips face or tongue (angioedema);
- Shaky movements and unsteady walk (ataxia);
- Skin rashes;
X- Unpleasant taste; (I think I can smell it too, everything smells like vitamins almost or metal?)
- Visual disturbances;
X- Upset Stomach/Vomiting (only twice I feel fine now)



UGH!!!!!!!!!! can't wait for all this to be over with!!!! I have been havin insomnia very bad lately obvously cause it is 2:30 am here!!

by RCA759I, Nov 11, 2009 06:28AM
To: MayMayMeemers
Everything that you have checked off is common following a large dose of Flagyl (insomnia included). If for some reason this doesn't resolve within the next day, I would suggest that you consult with your family physician, just for your own piece of mind. You are clearly very concerned, and the reassurance of an MD may very well ease your mind. Again, these symptoms are well known reported effects. They will subside as the drug clears your system.

My personal opinion is that you are reading into matters excessively, and that you are disturbing yourself by doing so. However, if you feel the need to seek treatment for any reason, then you should do so.

-Ryan

by MayMayMeemers, Nov 11, 2009 07:09AM
To: RCA759I
Yeah, most likely...I had a M/c on oct 23 so I was upset about that. had started staying up later and later each night now I can't sleep at all!!!


I am sure I don't have an overdose,  if I did I would be throwing up alot more then I did.
I will take your advise however I may just call the er and ask them what I should do...hate to think about going in when there would be nothing wrong with me. My poor boyfriend is suffering form my panic attacks and thoughts of me dying.
this isnt the first time, infact...before I found out I was pregnant I thought I had a cyst. =/ came up being pregnant.

second time was when I went to the er the 3rd time and they said I had an abnormal palp on my ecg so I thought I had wpws cause he wrote that down and circled it

after I thought a brain tumor and all the fun stuff..

Hypracondriac? most likely...

I started having bad panic attacks about a 2 weeks ago when I went to the er the first time for feeling dizzy...thats when I freaked out! I was walking to wal-greens and all a sudden got paniced, felt dizzy ect (was still pregnant) I lost the baby the next day and I went BACK to the er cause i didnt know what to do I had never been pregnant nor ever had a mc obviously!!

right after that I thought of these


infection
Animea
dehydration
low blood sugar
Heart problems
blood clots
brain tumor
and tons of other things
it was monday night when I freaked bout side effects and over dose
now I am just worried about over dose or something else wrong


so yeah....panic attacks, hypercondriac.........insomnia, i have it all right now!

heck, I have been awake since yesterday 10am and it is 5am here now horrid!!!!anyways..gonna try to sleep. If I can..... =/ again thanks for your major help!!! =)

by Strong103, Nov 27, 2009 03:31AM
To: MayMayMeemers
Hey I am going through the same thing right now. Did your symptoms subside after medication wore off?

by MayMayMeemers, Nov 30, 2009 01:01AM
To: Strong103
Yes, the symptoms vanished very wuickly after. I donot recomend Metronidazole in a 2000MG. way too many side effects!!
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