Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum.  ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
 | 

xanax vs. xanax XR

by kbennj, Jan 31, 2009 11:24AM
does the XR one work better?  I am finding regular xanax (.25) doesn't last past 4 hrs especially if you eat.  
Member Comments (3)

by HHSLK72, Jan 31, 2009 11:49PM
To: kbennj
The answer is...it depends on the frequency and duration in which it is to be used.

If you are taking Xanax for a short duration of time (less than four months), the XR formulation would prevent the majority of the peaks and troughs that you are experiencing with IR Xanax (rebound anxiety). The XR version is time-released, and has a smoother duration of onset and a more prolonged duration of action. This helps to minimize the "rollercoaster effect".

As with any preparation of Alprazolam, it is not intended for long-term use (use in excess of four months). The risk of the development of tolerance is very high. Once tolerance to the effects of Xanax develop, it will no longer be effective. Increasing the dose will temporarily reestablish efficacy, however, this would be short lived.

If you need a long-term treatment option for your anxiety, Klonopin or Valium are superior. Klonopin is indicated for panic only, while Valium is indicated for generalized or "tension" anxiety. Unlike Xanax, neither of these agents appreciably lose their efficacy over the long-term. This is a function of their long half-lives (36 hours and 24 hours respectively). In comparison, Xanax carries an 11 hour half-life, and does not accumulate in your system. This lack of accumulation is what induces "interdose" and "rebound" anxiety between doses. It is also what induces the development of tolerance. Since Klonopin and Valium accumulate, the drug is held at a consistent level in your system. And since it is always present, you would have 24 hour coverage against the symptoms of anxiety/panic with the latter two.

In short, Xanax is not indicated for long-term use (in any preparation).

by kbennj, Feb 01, 2009 09:29AM
why don't Drs perscribe valium anymore then, why do they immediately jump to xanax?

by johnboXR, Nov 15, 2009 08:33PM
To: kbennj
Doctors are real quick to put someone on xanax for some reason, I think they do this because they know its for short term, so one of these days hes gonna cut you off and then you'l be in withdrawl hell. You should ask your doctor to put you on Klonopin it is used for longer term and is easier to withdrawl from.
Related discussions
Post Comment
To
Comment
Post Comment
Recent Activity
doctora commented on photo
5 mins ago
doctora commented on photo
35 mins ago
doctora commented on photo
47 mins ago
rogelio63 commented on photo
49 mins ago
rogelio63 commented on My BFF is going away...
50 mins ago
doctora commented on photo
53 mins ago
mama23babies uploaded new photos
1 hr ago
TrudieC commented on photo
1 hr ago
RSS Expert Activity
What You Don't Know About Breathing...
Nov 24 by Steven Y Park, MD
Thanksgiving
Nov 23 by Thomas Dock, Vet. Technician
Snoring As Your Internal Smoke Alar...
Nov 22 by Steven Y Park, MD
Community Members