What to do next?

I suppose you could just call me an idiopathic mess at the moment! Since January, with new developments weekly:
diarrhea, night sweats, Alopecia, Rash on ears,
twitching/tremors(legs, hands, neck),

[Kevin Pho, MD]

Hello - thanks for asking your question.

You have clearly had a comprehensive workup.  CBC, ESR, TB, Hep-panel, CPK, anti-thyroid, protein, RPR, ANCA, ANA profile, metabolic panel, hepatitis panel, hla-b27, stool cultures was non-revealing.  Scheduled for a cholecystectomy due to acalculous biliary pain.

Without examining you, it is impossible to say what is going on.  There is no specific pathology that is ordered - if there is anything to be found, it will be done routinely.  

Some other thoughts.  I would consider some imaging tests to evaluate your symptoms.  Diarrhea since January should be evaluated for chronic causes such as inflammatory bowel disease or colitis.  Endoscopy such as colonoscopy or flexible sigmoidoscopy should be considered.

For your neuropathic pain (i.e. the shock-like pains), make sure that the potassium is not so elevated as to cause this - elevated electrolytes can certainly cause neuropathic pain.

I would have the freckling be evaluated by a dermatologist.  Any rapid appearing skin lesions is concerning.  A biopsy would give a definitive answer.  

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Thanks,
Kevin, M.D.