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methotrexate and coldsores

methotrexate and coldsores

I have psoriatic arthritis and had been in remission for over 3 years until a fall late last year.
I have been back on methotrexate, oruvail and sulfazaline (i think that's how it's spelt) and i have also had recurring coldsores for the past 4 months.
I have heard the methotrexate causes the coldsores, i would like to cease it if i can. I don't feel run down or burnt out so am a little confused as to why i am still getting these horrid sores.
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I found this information that you may find helpful:

Question: What Causes and Heals Mouth Sores in Arthritis Patients?

•What can cause mouth sores in arthritis patients?
•Can any medication cause mouth sores or is it more common with certain medications?
•Are there other reasons for mouth sores (i.e. dry mouth in Sjogren's syndrome)?
•What treatments help eliminate mouth sores?
•Are there any preventative measures one can take?

Answer:
What Causes Mouth Sores?
Oral ulcers or mouth sores develop on the palate, under the inside of the lips or inside of the cheeks. They are not uncommon in patients with arthritis due to medications. For example, medications which often cause mouth sores to develop include:


•NSAIDs
•methotrexate

What Treatments Help Relieve Mouth Sores?
In patients on methotrexate, taking daily folic acid, 1 mg or greater may reduce the incidence of mouth sores. If the problem persists, folinic acid (leucovorin) taken 8-12 hours after methotrexate may help without affecting the efficacy of methotrexate.

In patients who develop mouth sores on NSAIDs, consider switching to another NSAID or different therapy. Other treatments which may work to heal or prevent mouth sores include:


•supplemental folic acid (have your vitamin B12 checked as increased folic acid may mask occult B12 deficiency)
•yogurt
•acidophilus

Local steroid therapy such as kenalog in orabase may help for a few ulcers, while a combination of dexamethasone/benadryl/maalox in a 1/1/1 solution (swish and spit out) may ease the symptoms of multiple ulcers and help healing.

What Other Arthritis-Related Conditions Can Cause Mouth Sores?
Oral ulcers may also be a sign of lupus and reactive arthritis. The ulcers associated with lupus are typically painless.
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