Isotretinoin is known to have potential hematoligic (blood) side effects, which could affect your body's immune system. The drug may cause anemia, thrombocytopenia, neutropenia, and there are rare reports of agranulocytosis. Neutropenia is an abnormally low count of neutrophils (white blood cells). White blood cells are what helps your immune system fight off infections.
A symptom of neutropenia (low white blood cell count) may be infection. If you are concerned that your immune system has been altered by taking isotretinoin, you should visit your doctor to get a complete blood count test. This test can determine if any of your blood counts, such as your white blood cell count, are not within the normal range.
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