I developed hives 2 months ago. They are worse in the morning and fade through the day. I saw an allergist and tests were completed. I have a positive ANA with titer of 1:640. All other tests were negative: TSH, C3 complement, C4 complement, A Microsmal AB, Anti Thyroid Antibody, Anti-DNA, Sjogren Antibody Anti-SSB and Anti-SSA, Anti-ENA Ribonucleprotein, Anti-ENA Smith Antigen, Anti-Ribosomal P Antibody Ribosomal P Protein AB. I took a prednisone schedule, they cleared up, and went I tapered off them I got the hives back. I do have a history of hypothyoid and PCOS for 18 years. I have no allergies and I never get sick (probably 5 times in my life). I am stress-free and exercise 5 times a week. The only time I ever had hives before was 20 years ago as a child. I saw an allergist then and there was no found cause. I took Benedryl and they were gone in 4 months. I have no idea to any cause then or now.
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