DON'T TAKE IT UPON YOURSELF TO GET OFF THEM! I have a friend with Lupus. She was taking high doses of Prednisone for years. She suddenly decided that she didn't want to take them anymore, so she just stopped. She fell into a coma for 3 months. A doctor has to wean you off Prednisone, if it's necessary for to get off it.
I don't know why you are taking the prednisone so it is hard to say. I know it is used for many conditions to control inflammation. That would be something to ask the doctor prescribing the medicine. I was on 80mg/day at one time...now I go between 5mg and 20mg when I get a bad flareup. Are you monitoring the food you eat and avoiding things that increase inflammation? I will be praying for you, God bless.