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2 parents carry HLA-B27 gene
What are the chances that a child born to 2 parents carrying the HLA-B27 gene will have Ankalosing Spondylitis?  One parent has the disease.
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4173379 tn?1355360151
Here is a link outlining the risk assessment for children...

http://ghr.nlm.nih.gov/handbook/inheritance/riskassessment

Hope it helps...take care..C
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4781880 tn?1359395334
I was told that if one parent had the gene then there was a 1 in 4 chance of passing it onto a child - my dad had AS however he went undiagnosed until an accident on hoiliday resulted in an MRI scan - mine was discovered at age 20 - and being female I was really unlucky as the vast majority of AS sufferes are male.  
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