AUTOIMMUNE DISORDERS COMMUNITY
Dr. Nicholson: + ANA with centromere antibodies, elevated ferritin - HcT

Dr. Nicholson: + ANA with centromere antibodies, elevated ferritin - HcT

I have had a positive ANA with centromere antibodies since Oct 2009. I do not present with any skin symptoms so the Mayo Center is leary to DX me with Scleroderma -  although rare, they did say Since Scleroderma was a possibility. The diagnostic testing did reveal: raynauds, esophageal dysmotility (failed 30% of swallows), some delayed gastric emptying, had an esophageal dilation, of course the +ANA and + ACA.  Symptoms are more rheumatological with joint pain, bouts of severe fatigue, hand pain, muscle weakness (no elevated CK), low grade fevers, arthritis in wrists, random swelling of hands and fingers. Mayo said go home till I got worse, then come back...Local rheumy said "You have Crest" and started Methotrxate due to swelling in hands. Now my most recent labs came back with a lowered Anticentromere at 3.0, an elevated Ferritin at 190, and an elevated Hematocrit at 47.... Is the ferritin directly related to an autoimmune response (acute phase reactant?) or do I need to pursue further testing? Also to note I have had a borderline hepatospleenomegaly during this period as well. With the elevated HcT do I need to pursue further testing? The rest of my ANA reflex panel is all negative, the only other oddidty is a protein gammopathy of Alpha 2....what do you think? Crest? Something else completely?
Related Discussions
Post a Comment
To
Comment
Post A Comment
Go
Blank
Weight Tracker
Reach your weight goal faster
Start Tracking Now
MedHelp Health Answers
Submit
Top Autoimmune Answerers
1530171_tn?1336156566
Blank
Nikodicreta
London, ON
434278_tn?1324709825
Blank
karajo
Spearsville, LA
1756321_tn?1337799323
Blank
Red_Star
Queensland, Australia
553995_tn?1332022440
Blank
Phtartist
Ocean, NJ
681148_tn?1285160820
Blank
FurballsMom
798555_tn?1292791151
Blank
LazyMoose
MN
RSS Expert Activity
1741471_tn?1336957856
Blank
LIVE WEBINAR TOMORROW!-SUPER BODY, ... Blank
May 22 by Michael Gonzalez-WallaceBlank
2126606_tn?1335910182
Blank
Fibromyalgia Awareness
May 11 by Clare Waismann Kavin, RASBlank
2126606_tn?1335910182
Blank
Opioid-induced hyperalgesia reduces...
May 03 by Clare Waismann Kavin, RASBlank