Autoimmune Disorders Community
Dysautonomic crisis causing Diabetic and Addisons flare?
Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Dysautonomic crisis causing Diabetic and Addisons flare?

Could autonomic neuropathy be the cause of diabetes type 1 and primary addisons? Two years ago I became a diabetic sugar levels 1 - 33mmol/L and a struggle to control as it will rise and fall uncontrollably. Then a year ago addisons with sodium lowest was 106 and potasium level of 7.4. This year my bladder became paralyzed and so the colon. Pupils dilate unevenly and heart rate dropped to 8 beats, Bp to 50/22 and it was a miracle I survived. Specialist previously said it is polyendocrine disorder and causing severe autonomic neuropthy when I think it could be the other way round neuropathy causing weird diabetic and addisons picture/show. could it...?
Blank
Avatar_m_tn
Polyendocrine also goes by names of APS, and is subdivided into types I, II and more. It's a catchall to designate endocrine disorders they often find together, but it's not a pure 'cause and effect' . In other words, diabetes doesn't cause addison's. Addison's doesn't cause diabetes.

What they have in common is autoimmune disorders. Antibodies that loyally spent their whole lives defending your body just decided one day to 'go over to the dark side' and start fighting AGAINST you! What nerve!

So they start chomping away at whatever organ they find the tastiest, and medicine can't stop them at the moment. That's why the current treatment is just to replace the hormones you can't produce anymore.

Have they checked for pernicious anemia? Reason I ask is it's associated with autoimmune polyglandular syndrome (that's the other nickname for the condition) and it has autonomic neuropathy as a classic symptom. Its an autoimmune disorder that destroys 'intrinsic factor' in your digestive tract so you can't absorb vitamin B-12.

This is a quote from Autonomic Neuroscience journal  - "The results suggest that vitamin B12 deficiency causes autonomic dysfunction with similar hemodynamic consequences and patterns of autonomic failure as seen in diabetic autonomic neuropathy. Defective sympathetic activation may be the cause for orthostatic hypotension, which is occasionally seen in patients with vitamin B12 deficiency. It is concluded that patients with orthostatic hypotension should be screened for cobalamin deficiency."

Read the abstract at http://www.autneu-journal.com/article/S1566-0702%2801%2900393-9/abstract

Related Discussions
2 Comments Post a Comment
Blank
Avatar_m_tn
Polyendocrine also goes by names of APS, and is subdivided into types I, II and more. It's a catchall to designate endocrine disorders they often find together, but it's not a pure 'cause and effect' . In other words, diabetes doesn't cause addison's. Addison's doesn't cause diabetes.

What they have in common is autoimmune disorders. Antibodies that loyally spent their whole lives defending your body just decided one day to 'go over to the dark side' and start fighting AGAINST you! What nerve!

So they start chomping away at whatever organ they find the tastiest, and medicine can't stop them at the moment. That's why the current treatment is just to replace the hormones you can't produce anymore.

Have they checked for pernicious anemia? Reason I ask is it's associated with autoimmune polyglandular syndrome (that's the other nickname for the condition) and it has autonomic neuropathy as a classic symptom. Its an autoimmune disorder that destroys 'intrinsic factor' in your digestive tract so you can't absorb vitamin B-12.

This is a quote from Autonomic Neuroscience journal  - "The results suggest that vitamin B12 deficiency causes autonomic dysfunction with similar hemodynamic consequences and patterns of autonomic failure as seen in diabetic autonomic neuropathy. Defective sympathetic activation may be the cause for orthostatic hypotension, which is occasionally seen in patients with vitamin B12 deficiency. It is concluded that patients with orthostatic hypotension should be screened for cobalamin deficiency."

Read the abstract at http://www.autneu-journal.com/article/S1566-0702%2801%2900393-9/abstract

Blank
Avatar_m_tn
By the way, when he says 'cobalamin deficiency', that's vitamin B-12
Blank
Post a Comment
To
Go
Blank
Weight Tracker
Reach your weight goal faster
Start Tracking Now
MedHelp Health Answers
Top Autoimmune Answerers
1530171_tn?1362547225
Blank
Nikodicreta
London, ON
434278_tn?1324709825
Blank
karajo
Spearsville, LA
Avatar_f_tn
Blank
elbamom
westminster, CO
1756321_tn?1364494483
Blank
Red_Star
Queensland, Australia
484160_tn?1343401521
Blank
OldFatChick
Dickinson, TX
Avatar_f_tn
Blank
nutrinut_bob
RSS Expert Activity
748543_tn?1371556709
Blank
Jaw like a Plane?
20 hrs ago by Hamidreza Nassery , DMD, FICOI, FAGDBlank
521840_tn?1348844371
Blank
When your child needs a Psychologis...
Jun 13 by Rebecca Resnik, PsyDBlank
1741471_tn?1369660473
Blank
NBA 2013 FINALS START TODAY- Train ... Blank
Jun 06 by Michael Gonzalez-WallaceBlank