MTHFR

Hi,
I am 38 & I have 2 mutations of MTHFR C677T & one mutation of PAI-1 4G/5G.  I am going thru fertility treatments, specifically donor eggs very soon.  I am very nervous about becoming pregnant & miscarrying.  I have normal homocystenine levels.  Do you find it necessary to treat with lovenox?  I understand this is a controversial topic.
I am currently take extra folic acid, & baby aspirin.

[Dinodog]

Hi Kricket212,

I am 50 & was recently diagnosed with the PAI-1 4G/5/G mutations.  My hematologist offered me vey minimal info at best so I have been attempting to educate myself on the subject.  

What I have recognized is the fact that this mutation seems likely to be a source of a lifetime of unexplainable events.  My children are now young adults, however my ob-gyn history was extremely remarkable for complicated events for which many facts had been hidden in my medical records.  I would be happy to share what I know or have experienced.  

Had I originally been made aware of this disorder long ago, potentially I may have experienced better outcomes with my pregnancies and other complications that are likely effected by these mutations.   I also test + for a single copy of the MTHFR A 1298C.

Would love to understand more.  I hope your treatment proves successful and pregnancy goes well!

[HollyTH]

Kricket,

How much folic acid do you take for your MTHFR?