Autoimmune Disorders Community
Positive ANA and SSB antibodies- Sjogren's?
Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Positive ANA and SSB antibodies- Sjogren's?

This past week my PCP ran an ANA at my request, to have it come back positive (for the second time). She also ran a more specific antibody panel, and the only result to come back positive was for Sjogren's/ SSB antibodies. Both were very weak positives, 1:40 with a nucleolar pattern and the SSB antibodies were at a 1.6.

At the moment I don't have any of the hallmark symptoms of Sjogren's (aka dry eyes or mouth), but I have been diagnosed with several health issues in the past six months: POTS/dysautonomia, afib (which has been ablated), and hypothyroidism. Is it possible to have Sjogren's with such weak positive lab results and without the classic symptoms, and is it possible that this (or some other) autoimmune disease is the root of all my other issues? Thank you very much!
Related Discussions
2 Comments Post a Comment
Blank
1056589_tn?1273750702
Hi,

I have all the classic Sjogrens symptoms.Dry mouth,eyes and nose...I also have neurological issues too. I have been diagnosed with Raynaud's ,chronic dry eye,Allodynia and migraine/migraine varients.
I have a med/high positive ANA 1:32 homogenous but my SSB was negative. I am going back to the rheumy for more tests in April.
Yes you can have Sjogrens with negative SSB antibodies.You are more likely to have more complications the higher the SSB antibody titer. There are other tests that are a bit more accurate. Salivary gland biopsy and also theres a tests that measures tear production too. Sorry I cant think of the exact name...

Take Care.....
Blank
Avatar_n_tn
RedAngel84, I dont have an answer for you but I was wondering if you found out more about your dx. I also have had a positive ANA and was positive for SSB antibodies; these were very high. I was also positive for anticardiolipin antibodies. Like you, I dont have any typical Sjogrens symptoms, but I do have a lot of health problems - including hypothyroidism and although I dont have POTS, I do faint frequently due to low blood pressure. I have had SIBO since 2006 and it always comes back and I have excessive fatigue and bloating and pain and some fibromyalgia-type pain.

I haven't seen the rhumatologist yet but will soon. If you have any updated info or a new dx since you posted this, please share it. Thank you.
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Autoimmune Disorders Community Resources
RSS Expert Activity
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating Control: How to St...
Aug 28 by Roger Gould, M.D.Blank
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
Top Autoimmune Answerers
434278_tn?1324709825
Blank
karajo
Spearsville, LA
1530171_tn?1362547225
Blank
TheLightSeeker
London, ON
1756321_tn?1377771734
Blank
Red_Star
Queensland, Australia
8221281_tn?1397574572
Blank
Pantx
Denton, TX
1340994_tn?1374197577
Blank
Caryopteris
Raleigh, NC
Avatar_f_tn
Blank
nutrinut_bob