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Remicade Humira Cimzia Enbrel -- Question/Comment regarding Side Effects (Crohn's, Inflammation & Arthritis)

by LR23, Jul 27, 2009 11:18PM
The TNF Blockers work really well for the reactive arthritis related to my Crohn's Disease [Crohn's Colitis].  However, I have found that to varying degrees Remicade and Humira give me the following side effects.  I am trying to find out if these are normal side effects and if anyone has found a way to manage them.  Physical therapy is not giving me enough relief at this point.

Pros:
Joint inflammation and pain are controlled
Significantly reduced sed rate

Side Effects:
Debilitating fatigue (Remicade but not Humira)
Mood swings and constant cranky, withdrawn feeling -- abnormal for me even when sick (Remicade but not Humira)
Deep muscle pain and tightnes (Both)
Terrible pelvic pain, testicular swelling and urinary issues (Both)
Pudendal nerve problems (Both)
Decreased testosterone and libido (Both)
Pulsating headache along ear, jaw and trigeminal nerve (Humira more than Remicade)
Jaw tightness (Remicade more than Humira)
High blood pressure and fast heart rate [sinus tachycardia] (Humira)
Loose stools and increased urgency (Both)  ---IRONIC since I'm taking this for Crohn's!!! ---
Hair loss, Folliculitis, Yeast Infections, Thrush and other skin infections (Both)

Any thoughts, stories or remedies would be helpful.  I'm willing to try anything reasonable to lessen these side effects.  I have tried pretty much all of the drugs available for Crohn's and Arthritis and the TNF Blockers while only partially helpful were by far the best.  I need to make this work!

Thanks.
Member Comments (1)

by cummings0309, Sep 22, 2009 10:12PM
To: Hi
Hi, My husband has been taking Remicade for almost 5 years now. He has completely changed in this time and has a terrible temper and mood swings which he used not to have. He also seems depressed at times. After he has the Remicade, especially the day after he is in a HORRIBLE mood. I am sure this drug is the cause, because he wasn't like this before he started taking it.
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