psoriasis causing uveitis and chronic fatigue?

Can anyone help with this? I have had Psoriasis since about age 11. I am now 47. Always has a little patch here and there. Always knees and elbows and occ. larger ones on legs. I know Psoriasis can be triggered with trauma, stress and infection. In the end of 2008 ans Jan. of 2009 I had 4 major surgeries and a huge post op infection. 6 months later I developed Uveitis of my eyes they say is from my Psoriasis, I have gotten new patches where I have never had them before and topical treatment is not working well this time, and I have severe fatigue to where I will fight to stay awake when talking to someone and driving is just not possible for more than 5 miles before I get sleepy.

I have been testing for Narcolepsy or hypersomnia for the excessive fatigue but no conclusive answer yet. Am on Pravogil which helps some. Taking huge doses of adderall (adderrall) XR and fast acting adderall (adderrall) twice a day with no help. Like taking candy. Cpap has helped since I also got sleep apnea about the same time. I am wondering with all the stress of the surgeries and the infection on my body it may be from the psoriasis?  I also have been having some stiffness in my fingers in the mornings, my Scoraticilias Joint (SI joint) has also gone out,memory and concentration are shot. Could I have psoriatic Atrhritis causing this?  All blood work neg. Anyone else with this? I know it is alot and am sorry but you can see why so confused...    Oh yeah. Also had MVA with concusion in 2006 fo also trauma there . Thank you everyone even if you cannot help.  

[TrudieC]

Auto immune issues can definitely rear their ugly heads after trauma like yours.  I've experienced similar and if we already have one type of auto-immune disease we can easily take on another.  

What kind of doctor ran your tests?  Are you seeing a rheumatologist?  I haven't seen fatigue as a symtpom of psoriatic arthritis.  Rheumatoid arthritis does have the fatigue with it and can take some time to show up properly in your blood work.  I would encourage you to ensure you are seeing a good rheumatologist for a thorough work up.  They can also determine if you might have Chronic Fatigue Syndrome or fibromyalgia which can cause similar symptoms.

[shelly62]

Yes I have seen them all. Rheumatologist, Dermatologist, Sleep expert. All are working to try to figure this out. Have had RA, FANA, LYMes, ETC and all neg. My sed rate was elevated at one visit and then boarderling next one so possible some imfamation somewhere. Wondering if I do have PA but just not showing much for symptoms yet. I will be getting off the Methotrexate in about 3 months and worried about relapse of the Uveitis. Guess we won't know till then. My sleep doc is sending me for second opinion now since last meds didn't do much for the Fatigue. Will let him know about the ? of PA then and see what he says. I think I am goingn to be one of those people that the docs just don't know what to do next and will just have to live with it . thank you so much for your response. I am wondering about Fibromyalgia at times but without the pain not sure that could be it. thank you again. I will keep watching this forum to see if someone else may have ideas or if I can help others.

[katarina777]

Taking so many stimulants can cause an adverse reaction where you actually become more tired over time. These stimulants, like Adderall (adderrall), and Provigil also suppress your immune system and it's harder to get oxygen, or breathe, at least for many people.

My son, who is also on stimulants, also has real problems like you with Psoriasis .

Also keep in mind that this may be a fungal infection, as that can make you feel terrible. Fungal infections is something American doctors do not know much about and tend to ignore. Sometimes, they even treat the symptoms with an antibiotic which makes it much worse? Kat

[shelly62]

thank you all for you comments. I see the sleep specialist again today and will be telling him Adderall (adderrall) seemed to have helped with the morning and evening excessive fatigue but did nothing with the cognitive issues. Probably goiing for another opinion. Waiting for Rheumatologist to call back to comment on the new stiff / achy fingers and knees to comment. Day by day I guess. If I find a miracle cure I will let everyone know. Update soon for you and take care.