After my last pregnancy (2006) I developed some kind of autoimmune disorder that affected my joints and has been tentatively diagnosed as Undiff. Spondylitis./AS or possibly seronegative RA. I've been on plaquenil for 4 years with great success and tramadol for pain management.
I am now pregnant again and have gone off of plaquenil entirely and have reduced the tramadol intending to discontinue that as well.
My question is concerning remission during pregnancy. If I do NOT go into remission during pregnancy am I doing more damage by staying off the plaquenil? And is there *any* chance that this pregnancy could get rid of the autoimmune disorder altogether?
It has always interested me that the anti-malarial (antimicrobial) drug plaquenil is effective in many cases of RA and Ankylosing Spondylitis.
If RA and AS are caused by or affected by chronic infections, then you might expect such results. Interestingly, the Road Back Foundation (a RA support foundation, www.roadback.org) has for some time suggested that RA and associated diseases are caused by microorganisms that stimulate an inflammatory immune response in the synovia and joints.
Also interesting is the observation that many patients undergo remission during pregnancy but slowly revert again after the pregnancy is over. During pregnancy a women's immune system is under more control, probably to prevent an immune response against the fetus. This may explain the apparent remission of RA and other autoimmune diseases during pregnancy.
As to the question about whether pregnancy could eliminate the autoimmune disorder, I strongly doubt this notion. As mentioned above, in most cases the autoimmune disorder slowly returns after the pregnancy ends.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.