I had to be hospitalized after starting Cymbalta, it knocked me over the edge. I was advised never to take and AD's in that category, other the Wellbutrin which has a long track record of positive studies. I became hypomanic and suicidal, I couldn't think straight. I became much calmer off those meds, I was switched over to Lamictal, a life saving drug for me.
I asked my Dr today about antidepressant & estrogen & he'd never heard of such a thing. He did say AD need to be given w/caution to people w/bipolar because of the risk of rapid cycling but that each person is an individual case & that also needs to be taken into consideration. As for me I actaully have to take 2 AD in the winter months here in michigan because I tend to have more depression,but come April I get off 1 of them. I am also on 2 atypical mood stablizers.It's been mostly trial & error for me but we finally found what works & haven't had any major episodes ( manic or depressed) in over a year.
I was under the impression that AD's were known for increasing cycling in both men and women. I have certainly read posts of men who have had this experience so it is not exclusive to women. I would be interested to know more as I have been recommended an antidepressant to add to the mix and have been holding off due to aprehension because of the negative things I have heard.
My doctor, what I've read by other doctors, and my personal experience is that bipolar people (men and women) in general should only take ADs with great caution.
Every AD I've taken (TCAs and SSRIs) except Wellbutrin have caused me to cycle rapidly and precipitate mixed states and [hypo]manias. I'm good on a mood stabilizer alone.
I think I will ask my psych. about this when I go see him today. I have bipolar I & I am on antidepressants too because I also get depressed, severely, when I'm not on them. But I am now postmenopausal. I do know that before my hysterectomy I was very much rapid cycling. I do not take hormone replacements so I havve very little estrogen. This was something I'd never heard before but will be interested in finding out more. I'll let you know what I find out.
That's interesting. I wonder if AD's cause men to rapid cycle? Anyone? I know they did for me, and I am female.