Diagnosed w/bipolar within the past year and doc has me on 1500mg depakote and 300mg seroquel -- I'd say they give me 80% relief from my symptoms, I don't feel 100% well. But I feel like I'm in a fog all the time, I sleep 10-12 hrs. a night and when I wake up I just don't want to get out of bed and he gave me provigil to help me stay awake during the day. Also, I've gained 20 lbs! I asked for different meds but he doesn't want to try anything else which may not work as well as the depakote and seroquel. Am I doomed to feel like this the rest of my life, or should I insist on trying some different meds, knowing I may have to try several of them before I find anything that helps my symptoms. Also, the darn meds cost so much -- I do have health insurance but it only covers part of the cost.