I am on 500mg of seroquel XR, down from 600mg. It differs from the quick release because it doesn't sedate you as heavily after taking them, rather it has a more consistent effect. This I found difficult to get used to at first having become somewhat dependent of the heavy sedation for sleep.
It took a lot of getting used to, and I still suffer from side effects at times but I persisted with the medication, when others might have given up (?). The side effect profile is similar to other atypical AP's and really there is no way to forecast whether you will experience any.
A lower dose can help with sedation/sleep which can help rectify upset sleeping patterns (quick release better for this), and higher doses act as an antipsychotic/mood stabiliser. I needed at least 500mg to adress the paranoia etc and am happy to remain (for now) at this level. My mood is generally better as well. It is difficult to tell whether the improvement would have happened naturally because the spring usually has a beneficial effect on me as well for some reason.
My advice is to taper on slowly so you get used to it's effects, sedation will usually get more tolerable as you get used to the drug. Good Luck.
I am currently on Seroquel XR and wish I could get off. Remember, everyone is different and my problems may not happen with you. Long and short is that I don't trust the psych dr that prescribed in to me and so I'm trying to start over.
I thought I would wean myself off and started to do so by taking one pill every other day instead of every day. I beginning to think thats not such a great idea. I'm having difficulty dealing with things, coping, sort of obsessing on things I know I have no control over. I think as of today I'm going to go back to my prescribed amt until I can get a new psych dr (can't be until Sept because of dr availability in my area).
Seroquel is an antipsychotic that is an effective mood stabilizer and FDA approved for that purpose as well. The short term side effects of concern are generally weight gain and sedation and short term movement disorders (which can be treated with a side effect pill). The long term side effects of concern are diabetes (which can be managed by regular blood tests and maintaining a proper diet) and long term movement disorders (which your psychiatrist can test for). This side effect profile is the same for all atypical antipsychotics (with Abilify and the other SDA's Fanapt and Saphris having a lower risk of weight gain). You should look at the medication brochure or website and discuss it with your psychiatrist. Just because you had some rare side effects doesn't mean you will acquire others. Its best not to generalize but to inform yourself and discuss any concerns with your psychiatrist.