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Wellbutrin to 5-HTP

by GG4362, Dec 10, 2007 12:12PM
Tags: irritable
I am taking 300mg of Wellbutrin after being on Zoloft for months (bad side effects there).  While Zoloft helped with my irritability, I could not handle the exhaustion or weight gain.  Wellbutrin has not helped with anything except the low-energy level (that is great now).  I am so mean I can't stand myself and I havem't lost any weight (even gained a few more pounds).

So a friend said her doc suggested 5-HTP.  I bought some, but I need to know if I can take it along with my 300 mg of Wellbutrin.  I am thinking of getting off Wellbutrin altogether but am not ready to start the weaning-off process without some alternative.

Any advice or info on 5-HTP and Wellbutrin together would be a tremendous help. Thanks so much!
Member Comments

by angelinamarina, Dec 11, 2007 03:36AM
UM, i would NOT take them together.  You could end up with seretonin syndrome which is a very horrible thing.

i had the start of ss once and i was so out of it i just sat in a chair and vomited.  It was really a bad thing.

I guess if you wanted to try it you could watch for signs of ss....google it.  I would ask your doc though.  

I just read a story about someone who took fish oil (omega 3's) with an antidepressant and got ss.

-angi

by stefa222, Aug 07, 2009 03:40PM
To: GG4362
Um, you can take them both together.  The reason why is because Wellbutrin works completely on dopamine and norepinephrine (sorry for the spelling) and Zoloft works on serotonin.  Wellbutrin is very commonly used as add-on when people don't respond well to SSRI's.
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