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What's the best mood stabilizers??

by Shani80, Sep 26, 2008 05:12PM
I was diagnoised with Bipolar Disorder this spring, and I have been taking both Zoloft and Depakote. My question is: " What is more stronger or more better, Lithium or Depakote??
Member Comments (8)

by Jikan, Sep 26, 2008 06:35PM
To: Shani80
Namaste,

There are of multitude of medications that are used as mood stabilizers with lithium and depakote being the primary ones.

Both are good at controlling symptoms, but lithium puts restrictions on your diet and depakote doesn't. But depakote can cause considerable weight gain.

If your doctor placed you on depakote, he/she did so as the first line of defense and will try other mood stabilizers if depakote does not work.

Different medications effect individuals differently so there may be a need for a change in medication and/or dosage.

The main thing is to be patient becase it may take some time to find the proper combination of medication(s) to control your disorder.

Let us know how you are doing and take care of yourself!

Michael

by monkeyc, Sep 27, 2008 01:11AM
I would like to call out the comment that Lithium puts restrictions on your diet.  It does not..

The myth that all patients who take lithium gain weight or need to change diets or restricts them is a favorite of some doctors and online sources, in fact other MS drugs are far more likely do do that (you noted Depakote which has almost guarentee of weight gain )  - Ive taken lithium for over 2 years now and have not gained weight and it has not restrcited my diet on bit - I eat what i want when I want and I can even drink alcohol as long as I am moderate and stay well hydrated.  There are not many MS that will give you the ability to have a glass or wine or a beer every now and then without serious problems.  (not that drinking is a reccomended course for BP's, I am lucky in that I dont have an issue with alcohol and dependancy - if you are going to drink alcohol SPEAK TO YOUR DOCTORS)

There are reasons why you may need to modify your diet with Lithium if you do not maintain enough salt in your body or are on a low sodium diet but the main difference lithium will be for most patients is an increase in water consumption as proper hydration is vital.

Too many people read side effects lists and think Lithium must be some horror drug - when the reality is it has been around for over a century and thus the list of noted side effects is going to be large but Lithium is safer than many MS drugs and particularly some of the Anti Psychotics which have side affects that are terrifying to read about.

The main reason why Lithium isnt prescribed as often as it used to be is simple (and most honest pdoc's will tell you this) - its generic and cheap and pharma companies dont make any money from it.

No it wont work for everyone and all drugs need to be prescribed by a doctor I wouldnt use a doctor who let me choose my own meds anyway.  

Sorry but I often see a lot of people around the traps who are anti lithium for no real reason other than their doctor told them the old one about weight gain and diet restrictions before putting them on a drug with the same effect that costs 3 times the per dosage costs and has the exact same side effects as Lithium or worse.

by PenelopeAnn, Sep 27, 2008 03:24PM
Ditto on what monkey said. I think I have been on every mood stabilizer and the one I am on now is the one that worked miracles for me. I take Lithobid. It is the slow release form of Lithium. Many years ago, I was tried on regular Lithium and had severe tremors before I could get to a dose that would help my moods. The others either didn't help, or they had intolerable side effects- I'm just one of those people. The mood stabilizers I've been on are Tegretol, Neurontin, Lithium, Depakote, Topomax (topamax), Trileptal, Lamictal, Abilify, and now Lithobid. I love Lithobid. I haven't noticed any side effects.

by jimgreg, Sep 27, 2008 09:10PM
To: shani 80..
the mood stabilizer has to be the one that works for you..some might not work for someone on here but then it might be the best for you..now i was put on lithium..i got lucky with it..it helps me and no side affects yet..i only been on it 7 weeks...lithiem is a good me and very old at that..i been studing on it ..they have had alot of years to study this one..wheres another me wasent studied as long..i was on seraquil for 2 yrs it helped me sleep and calmed the manic but not as good as the lithium..lithium has alot for you to learn about..HEY JUST ASK ON HERE THERS ALOT OF US ON IT..LIKE MONKEYC HES BEEN ON IT FOR YEARS AND LOVES IT..I THINK THIS WOULD HELP YOU OR WHOEVER...thanks for listing   james  anytime call on me

by Jikan, Sep 27, 2008 09:18PM
Namaste,

Apparently, my comment concerning restrictions on diet was taken too literally and referred to hydration and sodium diets. Sorry for the confusion.

Michael

by monkeyc, Sep 28, 2008 01:29AM
To: Jikan
Michael I did not mean to come off as attacking I just grow sick and tired of the anti lithium attitudes I see in some places in favour of X and Y drug and I was having one of those days, apologies if this sounded harsh.

However when you say Diet Restrictions its going to be taken literally as it implies Lithium places you on a restricted diet which it does not in 99.999% of cases - this is the problem, people read that and go I wont even think about asking if lithium might work cause it makes you fat and you cant eat what you want and thus they miss the oportunity to ask about a drug that is not only cheap its also very effective and unllike many of the new drugs also not psychoactive.

As I said I was touchy but from where I sit there's often a negative anti lithium bias in Bipolar forums and hey its hard not to understand why with add for ablify playing on the page or when you go into the Doc's office and hes got the Lamactil Pen and the Geodon clock on his desk....

by irishwriter, Sep 28, 2008 04:33AM
To: shani80
i have been on lithium for two months now 1200 and blood level .97. I have no side effects, just drink a lot of water and was able to have a few drinks at wedding i attended. my only problem is that it is taking ages to kick in for me. am told it can take a long time so i'm trying to be patient. you need to find the meds that work for you. that's one of the downsides (and there are upsides!) of this disease in that the treatment is so individual. I have been living with this for thirty years and over the years tried many different treatments but this is the first time on a mood stabiliser so i keep on hoping it will work sooner rather than later. best of luck with whatever you start taking, i hope it works for you.

by cowgirlnerd, Sep 29, 2008 12:30PM
To: shani80
I am also new to the diagnosis of BP, but my pdoc put me on Lamactical and it's been really good for me.  Of course, I haven't taken anything else, but it has stabilized my moods so I don't have suicidal thoughts these days, and my mania is a lot less than before.

My advice is to ask your pdoc on ALL of the side affects that might occur, and discuss the problems you might have had with other medications in the past.  Also, if you begin taking a medication that makes you feel, at all, not well, or have irrational thoughts, contact your ER or pdoc, right away.  Sometimes it's, honestly, trial and error to get the right combo.  

I took every anti-depressant, anti-anxiety, etc., imaginable until getting this diagnosis.  
Bottom line, ask questions, ask questions, ask questions, and let your pdoc know if your meds are not working for you.  What works best for you - that's most important.  It might take awhile to find that combo, so be patient and chin up.  

Best of luck!


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