Why are the doctors n here so ill-informed about this issue? I have bi-polar disorder and have been taking 200 mg od Zoloft for years. On two different occasions, I ried to use Unisom to help me sleep. On both of those occasions, I came very close to a full psychotic split.
Upon checking with my Psychiatrist, I was told to NEVER mix unisom with Zoloft. Benedryl is OK, but there is a tremendous amount of antecdotal evidence out there about the dangers of Unisom and Zoloft.
Please try anything else before Unisom, or talk to yur Psychiatrist.