raw adrenal glandular on bi polar

mr friend recently took himself off trazadone, and was taking raw adrenal glandular capsuls 4 wks . he was told it would be good for stress. he recently went coo coo and left home .  could the adrenal caps( from swanson )  have triggered this .  he usually tends to be more depressed but doesnt want to take some meds that effect ejaculation never saw this side of him befor in the year and half i knew him.   suggestions please.

[ILADVOCATE]

If he was taking any natural remedy without a doctor's prescription especially one that could change hormone levels that is never a good idea and an abnormal change in hormones can cause mood changes and/or psychosis. He should speak to his doctor again as not all anti-depressents would have that effect you speak about.