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Elevated Immunoglobulin. IgM. what does this mean.
Hi.
I hope you can help me, Lately i have periods of fatigue, joint pains, bruising, etc..

I am persistant anticardiolipin positive, with a diagnosis of Antiphospolipid Syndrome.
I also am a sufferer of Graves disease, having two thyroid surgeries. But now take thyroxine due to no thyroid.

I was sent to an immunologist, who informed me that i had a high Igm Immunoglobulin in June 2008.
Also when she tested me again in December 2010, she found the same problem, an elevated Immunoglobulin IgM.

Please if anyone can shed some insight on this i would be grateful, as this one has got me stumped, and im not sure where this can point.
When i googled it , it came up Waldenstroms, this one i have never heard off.

I am very grateful for you looking at my post and if you could guide me or give me any information regarding this , i would be more than grateful.

Nicola
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Hi there. You have elevated IgM  levels which could indicate various conditions like macroglobulinemia, mononucleosis, early viral hepatitis, a parasite infection, rheumatoid arthritis or nephritic syndrome.  Since IgM are antibodies formed in response to a first time infection, high levels could mean a new infection. Antibodies to various antigens are a characterisitic of anti phospholipid syndrome like syphilis, cardiolipin antibodies and lupus anticoagulant. Discuss with your doctor these speculations and see if any better reasoning comes up. Take care and all the best.



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Like Nicola, I have had my thyroid removed due to cancer, a parathyroidectomy also and a hysterectomy. I have coeliac disease and symptoms of exhaustion, memory loss, high IgM. I am now in menopause due to hysterectomy becuase of low iron but symptoms not improving. I now believe all along I have had a thyroid disorder which had I know I could have addressed at a younger age an not be in this mess having visited doctors again and again only to be told I am fine! About to start on some Adrenal ReBuilder in the hope this improves my energy levels.
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