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MRI results please help

Went for pituitary MRI - pituitary was normal but....

MRI showed a few abnormal foci of t2 signal hyperintensity within the deep and sub cortical white matter of the frontal lobe. There may be additional tiny focus of t2 flair signal hyperintensity within the sub cortical white matter of the left frontal lobe. Nonspecific. Findings remain indeterminate.

No migraines or head trauma. I'm 31 years old. No hypertension or diabetes.

Been very tired lost over 30 lbs in less than a year without trying legs swelling and tender eyesight getting bad - fuzzy/blury (may just need glasses - long time since eye exam) anxiety and depression. Stay hot - night sweats sometimes. But hands and feet stay cold.

Weird blood test - some CBC showed low neutrophils, high lymphocytes monocytes baso and eos. Very high b-12 (over 1500)  - will have to gather up rest of tests - have had a ton...
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Avatar universal
The pull out for the quick shot meant you did not have a proper pituitary MRI aka dynamic.

Pituitary lesions tend to be on the smaller side. Size is not the determining factor - but the hormones they secrete. Yippee that is has not extended up or down - but that still does not mean you don't need a complete and total hormonal work up.

The white spots are beyond me as a layman - your doc really has to rule things in or out - and they can be very nothing up to something so since they can be anything, it would be nice that the doctor follow up on those to let you know he thinks those are ok for now, which it sounds like he says.

Re pituitary - I would really find a pituitary specialist IMHO.
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Avatar universal
So... The neurologist reviewed my MRI and sent an updated result- he did find a spot on my pituitary but - this is all jargon to me.... It says...
There's an intact but very faint pituitary bright spot marking the location of an intact neurohypophys on the Sagittal image. The only abnormality if the patient is secreting pituitary hormone would be an area off center dorsaly and inferiorly to the left on post contrast image 7. It is 2.5 mm in diameter.  This could be a small benign cyst or possibly a microadenoma. No involvement of cavernous sinus. No supersellar extension.  

Then goes  on to say he agree with original findings as far as the other white spots on brain but that these were in normal limits of my age...

So... Sounds like the white dots on brain are not too concerning. Would the small spot on pituitary be the cause of my problems or...???? Any info/advice/recommendations would be greatly appreciated.

The MRI was with and without contrast and they had me in MRI for bout 30 mins without contrast pulled me out have iv reveal quick then back in for about 15-20 mins...
Thank you!!!
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Avatar universal
The doc that runs this forum pops in and out - so hopefully you will get a response soon.

The white matter, from what I know as a layman - can be so many things from migraines to blood pressure to mini-strokes to MS - as the report says, it is very non-specific finding so your doctor has to rule things out based on your other tests and history.

Having been (and still!) a pituitary patient, and knowing many, a normal scan actually does not rule it out. Did you have a brain scan or a pituitary scan? Was it dynamic (and by that I mean with and without contrast, the contrast given so that you were NOT removed and images taken while the contrast given). If it was not dynamic, it was not a proper pituitary MRI.

Plus many a radiologist can miss a smaller lesion, sadly.

Any other hormonal testing of the pituitary?

I cannot comment on the CBC - but if funky I hope you see a proper specialist soon!
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Avatar universal
This started out as thyroid problem - thought it was hyperthyroid had borderline to slightly low tsh several times in past year and sometimes it was normal. But all other thyroid tests normal t3 t4 free ts thryroglobulin ab tsi thyrotropin and ultrasound of thyroid and iodine uptake scan - all normal except tsh slightly low sometimes (0.33, 0.38 etc)  so then they thought pituitary but apparently it's not...
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