Empty sella and familial osteopenia

35 years of empty sella, hi prolactin, testosterone injections, osteopenia, broken ribs and recently hip - and now at age 67 two of my children ages 33 and 36 flunk Dexa scans and are prescribed fosamax, which they refuse to take until hyperparathyroid is ruled out.  I get labs showing PTHs of 63/(15-65), 51 and 45, with ionized calciums of 5.2, 5.3 and 5.4 on scale 4.5 - 5.6.  Three endos and 2 GPs say it's all coincidental.  Should we get treatment in Europe?

[rumpled]

What about phosphorus and vitamin D, and urine calcium?
Have you been evaluated by a bone endo for other diseases (paget's etc.). You need a bone endo as not just any endo can do this.

Is your endo (or at least one of them) a neuro-endo?

[IONHI]

Thanks for your responses.  Nice call - those are the 3 labs I haven't checked yet. Monday I'm doing those 3 plus 2 more PTHs, one at 730am and the 2nd at 1pm, since my 2 highest previous PTHs were done around noon and the lowest was done at 745am, contrary to the predicted daytime dropoff cycle.

I am scheduling a MEN 1 dna test since that would seem to me to clarify my and my 2 children's varying, subjective lab results, and maybe force the temporizing MDs to come up with a definitive RX.  There are possibly 6 of us involved now, myself, my 3 children, and 2 grandchildren, and I remain underwhelmed and disturbed that 3 current and 10 past MDs and endos are content to insist on symptomatic fosamax treatment for all.

Maybe these medical professionals are related to the congressional and financial leaders of the past several years whose collective wisdom has brought us to worldwide credit collapse and a doomed, taxpayer funded big business bailout charade.

[rumpled]

I ask as my calcium is normal but my PTH tends low, and my urine cal tends high, phos high, and D low. I am borderline hypoparathyroid due to surgery but I had a pit surgery so I understand the empty sella.

It takes a lot to find a decent doctor. If you have it run in the family like that, it seems a no brainer that it is some form of MEN... I mean, geez... and there are better meds than fosamax out there. I would try to get one of the IV biophosphates as those tend to work better. You really need to get a bone endo.