High Pregnenolone

[Tig114]

Hi, I don't know if this is the right place to post this (and if anyone has a suggestion for a better spot, I can repost it)

Does anyone know anything about high pregnenolone?! My lab came back high, but none of the doctors have touched this and there just isn't a whole lot on the internet that I can find other than adrenal tumors. In fact, minus the whole tumor aspect, it seems like I might be better off with high levels considering all of the nice effects it supposedly has.

Any info would be great!

[Tig114]

Thanks! Hum dee hum, I found the same thing and I forgot to ask about it at my appointment. Ugh, well, maybe I'll remember today

[rumpled]

I found this in a medical paper:
"While 17-OH-pregnenolone was within the normal range in patients with hypercortisolemia due to Cushing's disease, ectopic ACTH or adrenal adenoma, 4 of 6 patients with an adrenal carcinoma had elevated levels of this precursor. Thus, elevated plasma 17-OH-pregnenolone levels in patients with Cushing's syndrome indicate adrenal carcinoma, although a normal value does not exclude this diagnosis. "

I don't know why your doctors have not done further testing. I would ask.