Aa
Aa
A
A
A
Close
765439 tn?1292960414

got my labs PLEASE read....

finally got my labs, id appreciate if you guys can read them...the columbioa endo claims I dont have an endocrine problem...but some of my labs are off! including cortisol and creatine!..please read them all if you have time and give me input on my next step!

creatinine w/egfr
creatinine 1.08 (.8 -1.30)

creatinine clearance
creatinine random urine 1826
creeatinine 24 hr urine 2.92 OUT OF RANGE (.63-2.50)   also says H
creatinine clearance OUT OF RANGE! 188 (85-125) also says H

cortisol free urine 70.4 OUT OF RANGE (4.0-50.0)
creatinine urine 2.96 (.63-2.50) performed by tandem mass spectometry

thats just the cortisol and creatine...which alone is out of range.....now here's everything else

cortisol 10.6 ref ranges 8:00 am (5-25)   4 pm (2-12)   post stim (25-50)   min normal increase -8   overnight  dexamethasone supp <5

ESTRADIOL- 22 (10-50)
fsh 2.9   pre puberty (<2) (post puberty (<10) so at 21 my numbers almost at the pre puberty level!!!!!!!!!!!!!1
LH 2.0 pre puberty (<2)   post puberty (<10)......IM AT PRE PUBERTY LEVEL

testosterone TOTAL- 535 (270-1070)...im mid range which isnt terrible but at 21  i feel i should be higher...but atleast im midranged.

basic metabolic pane
sodium 140 (136-146)
potassium 3.9(3.6-5)
chloride 100 (102-109) OUT OF RANGE!
co2 26 (24-35)
bun 13 (7-20)
glucose 65 (70-105) OUT OF RANGE
creatinine 1.0 (.6 - 1.2)
calcium 9.3 (8.7- 10.0)
T3 159 (94-170)
ferritin 55 (29-248) this seems low to me!
cholesteral 193.....im shocked this is fine...although almost above 200.

triglycerides 70 (30-200) THIS SEEMS LOW TO ME
hdl cholesteral 46 (40-59)
ldl cholesteral 133 (<130 is desireable) (130-159 borderline high)
t4 8.39 (5.41 - 11.66)
t4 free  1.21  (.7- 1.24)
tsh 1.13   (.32- 4.05)
Growth hormone- .29   range is less than 5......this seems low.....to me
prolactin 2.8 (2.5-17.0)
somatomedin c  267  (127- 424)
ACTH-  9 (7-69)........I SEEM LOW????
VITAMIN D 125 dihy 62  (15-75) ...ive been taking 10,000 units  a day...yippppe im not deficient!
vitamin d 25 hydrox......58 (30-80)...this is the ebst test....id lie to be at 70-80
HEMOGLOBIN A1C 4.8  REF RANGE 4.6......SO AGAIN I MOUT OF RANGE
glucose fasting 76 (70-105)  i didnt fast for any test?



there's some other numbers if someone wants to know mcv..or stuff lie that...i dont know if they are important..

PLEASE READ THIS....AND HELP ME.....MY NUMBERS ARE NOT NORMAL...MY HEMATOCRIT/HEMOGLOBIN IS ABNORMAL ION EVERY TEST  ITAKE.... my throid used to be 3.22 for my tsh now its 1.13?? i prefer it at 1.13 i  suppose but whys it changing really

thanks for any help....this took forever to type, but i hope my friends on this board will have some info for me....and reassure me im not crazy, and i have something going on here

if she would have done the hematocrit lie itold her that would be out of range also.
32 Responses
Sort by: Helpful Oldest Newest
765439 tn?1292960414
ok i made a mistake these labs were from april 20,2010.....which i guess makes my cholesteral raise even worse ha

but anyway, it says NONE next to ''collected''
but next to reported it says 12:45......those stupid techs didnt record a collected time -_-
Helpful - 0
Avatar universal
The time of the test should be on the lab slip.
Usually when you are high, one feels a lot better - cortisol is an anti-inflammatory and covers a lot of symptoms - hence why it is given as a medication for  a lot of stuff. Food does not effect it. Some docs may look at it as borderline but most will not.
Helpful - 0
765439 tn?1292960414
it was an am test,so im assuming it was 8am? it was 2 years ago, and icant even remember what  i ate last night anymore


but is that result really fine? with my history isnt a number that is that high in the normal range still suspicious? i mean the range goes from 4-22 and i was 20.7 almost 21!

not to mention i always feel SO bad in the morning.

i dont see thart doctor anymore...ive been going to a new primary for a few months whos great.

Helpful - 0
Avatar universal
The first test is fine. What time was the test?
Cortisol goes up and down in normal people and it is a very time dependent test.
You can be normal then and high now - the doc should take the changes into consideration.
Helpful - 0
765439 tn?1292960414
what do you know!!!!!!!!!!

i was just looking at some old labs from feb 2009....and there is an AM cortisol test...20.7(4-22.0)


and wow my cholesteral has gotten a lot worse due to bad eating.......
it was 60 back then and now its 193(maybe higher now) hdl went down ldl went up tryglicerides went up 20


but yeah is the above cortisol high or is it fine cause its in range...take into account my current tests are high
Helpful - 0
765439 tn?1292960414
yeah  i think ill take it  as a positive that cortisol is low. high testosterone low end of normal cortisol and low prolactin makes a strong man

haha just messing around ;)
Helpful - 0
Avatar universal
I found this:
"Levels of prolactin that are below normal are not usually treated but may be indicative of a more general hypopituitarism. Low levels may also be caused by drugs such as dopamine, levodopa, and ergot alkaloid derivatives."
But since you are male, it is really not going to effect you so much that I can figure out - re periods etc. but when my prolactin was high, it really effected my mind a lot.

Low cortisol is deadly.
Helpful - 0
765439 tn?1292960414
ive eard that cortisol could e too low(which shocked me..i thought cortisol was bad) but this begged the question about the possibility of prolactin
Helpful - 0
765439 tn?1292960414
is it possible for prolactin t0 be TOO low?
as a male im glad its low but is my level too low for a 21 yr old male
Helpful - 0
765439 tn?1292960414

by horselip
, Nov 19, 2010 11:39AM
Two comments-
One a correction to something i said above low chloride can mean hyperthyroidism
and #2 You did not have a stim test right? What do you mean Rumpled about normal result on the dex test?


yeah thats what  iwas wondering originally.
Helpful - 0
Avatar universal
Hey! I"ll put that down on the app next time! Good one!
Helpful - 0
596605 tn?1369946627
You only have one things worng- Your endocrine system :-)
Horsey
Helpful - 0
Avatar universal
It is newly published, at least.
Yeah, I would be a great rat except they only want them with one thing wrong.
Helpful - 0
765439 tn?1292960414
yeah, i dont consider that a new finding...jsut another finding that has been known by the community butt aken ages to figure out by the medicalsystem....im sure YOU knew this already -_-.

btw that's horrible that you were denied by nih.....i cant think of a peerson who could have had a more mutally beneficial case with them. youd make a great lab rat....lolo
Helpful - 0
Avatar universal
This just came out:
"High Prevalence of Normal Tests Assessing Hypercortisolism in Subjects with Mild and Episodic Cushing's Syndrome Suggests that the Paradigm for Diagnosis and Exclusion of Cushing's Syndrome Requires Multiple Testing.


Summary

Many Endocrinologists believe that a single determination of eucortisolism or a single demonstration of appropriate suppression to dexamethasone excluded Cushing's syndrome, except in what was previously thought to be the rare patient with episodic or periodic Cushing's syndrome. We hypothesize that episodic Cushing's syndrome is relatively common and a single test assessing hypercortisolism may not be sufficient to accurately rule out or diagnose Cushing's syndrome and retrospectively examined the number of normal and abnormal tests assessing hypercortisolism performed on multiple occasions in 66 patients found to have mild and/or episodic Cushing's syndrome compared to a similar group of 54 patients evaluated for, but determined not to have Cushing's syndrome. We found that 65 of the 66 patients with Cushing's syndrome had at least one normal test of cortisol status and most patients had several normal tests. The probability of having Cushing's syndrome when one test was negative was 92% for 23:00 h salivary cortisol, 88% for 24-h UFC, 86% for 24-h 17OHS, and 54% for nighttime plasma cortisol. These results demonstrated that episodic hypercortisolism is highly prevalent in subjects with mild Cushing's syndrome and no single test was effective in conclusively diagnosing or excluding the condition. Rather, the paradigm for the diagnosis should be a careful history and physical examination and in those patients in whom mild Cushing's syndrome/disease is strongly suspected, multiple tests assessing hypercortisolism should be performed on subsequent occasions, especially when the patient is experiencing signs and symptoms of short-term hypercortisolism.
Affiliation

Division of Endocrinology, Metabolism, and Molecular Medicine, Charles Drew University of Medicine and Science, Los Angeles, CA, USA.
Journal Details

Name: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
ISSN: 1439-4286"
Helpful - 0
Avatar universal
When I say I failed, I mean I also suppressed so I had a normal result (although some were abnormally low). Even on dex-CRH which is a NIH gold standard test. NIH may not take you based on the dex - they are proponents, sadly, of the test. I tried to get in there too. But if your doc sends in all your stuff, you may be able to get in.
Helpful - 0
765439 tn?1292960414
when  say you failed all dex tests does that mean you had a noral result..or an abnormal one? aka did you supress or not? im guessing you supressed.

i just wish i could get into the rare disease clinic. i think they have the best shot at helping me.....plus theyre in maryland so its not far.
Helpful - 0
765439 tn?1292960414
i went to my primary doc today...who is the only doctor  i love....
and she reccomended me to call the rare disease clinic at nih...she said the cortisol looks high to her....and she agrees small tumors can cause problems.

shes a very caring doc....but obviously as a primary there's not much she can do
Helpful - 0
Avatar universal
If you suppress on dex, that is a normal result. So that may, in the doc's eyes, wipe out the abnormal UFC. If you do some research though, that test is kinda iffy to some docs, and golden to most - some use it as a test of location, some use it as a test of exclusion. Columbia obviously used it as a test of exclusion. I failed all dex tests (low dow, high dose, etc.) and still was Cushingoid - I know lots of people in that boat.

From what I see, it does not appear there is a stim test here.

As for the low chloride - I have that constantly. I was told it was not low enough to be a factor. This is from a website:"Decreased levels of blood chloride (called hypochloremia) occur with any disorder that causes low blood sodium. Hypochloremia also occurs with prolonged vomiting or gastric suction, emphysema or other chronic lung diseases (causing respiratory acidosis), and with loss of acid from the body (called metabolic alkalosis)."

I can make mistakes - I am far from perfect!
Helpful - 0
765439 tn?1292960414
i didnt think  i had a stim test, but figured sicne  i dont know what all the tests mean, rumpled might have thought  i did, and i trust her more than myself ha
Helpful - 0
596605 tn?1369946627
Two comments-
One a correction to something i said above low chloride can mean hyperthyroidism
and #2 You did not have a stim test right? What do you mean Rumpled about normal result on the dex test?
Helpful - 0
765439 tn?1292960414
thanks as well
Helpful - 0
765439 tn?1292960414
thanks horselip ;)
Helpful - 0
596605 tn?1369946627
Hi TD-
Here's my take:

-Your adenoma is probably not a secreter.

-The ACTH was borderline low

-The 24 hour urine cortisol was high
I think that this certainly justifies more testing of the adrenal axis in particular. Something does not seem right to me in this part of the testing

-Your Hematocrits and Hemoglobins are consistantly a little high. I would rec that Polycythemia family of conditions be ruled out.

-Lh and fsh are at the post puberty level and your testosterone in mid-range
So your sex hormones are probably good.

-Chloride 100 (102-109) Can be elevated with hyperthyrpoidism

-Glucose 65 (70-105) A little low, don't really know why but do you get hypoglycemia?

-Ferritin 55 (29-248) could be iron deficiency anemia, have to look at (MCV) the Red blood cell to see, *also I'm making a mental flag because you've been running these slightly high hematocrits and Hemoglobins.

Thyroid
-T4 free  1.21  (.7- 1.24)
tsh 1.13   (.32- 4.05)
Could actually be that you are hyperthyroid, could explain the low chloride and glucose
-You may be hyperthyroid but it does not look like it is pituitary in nature? I don't know enough about this but so other people think that other tests should be done?

-Somatomedin c  267  (127- 424) This is what is used to check your Growth Hormone levels

Horselip
Helpful - 0
2
Have an Answer?

You are reading content posted in the Brain/Pituitary Tumors Community

Top Cancer Answerers
Avatar universal
Northern, NJ
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Here are 15 ways to help prevent lung cancer.
New cervical cancer screening guidelines change when and how women should be tested for the disease.
They got it all wrong: Why the PSA test is imperative for saving lives from prostate cancer
Everything you wanted to know about colonoscopy but were afraid to ask
A quick primer on the different ways breast cancer can be treated.
Get the facts about this disease that affects more than 240,000 men each year.