Aa
possible Cushing's
I need someone's opinion,, please. Ok,, I had to take a Dex test because my Cortisol level was high,, 26.4 in a fasting state at 8AM . I suppressed super low I guess at barely 1.5. So the Endo I know is going to say I dont have Cushing's , even though my Primary thinks I do. So ,, what does this mean to have an abnormal suppression response,, the fact that it went extra low?? Im so confused.
Make sure you get copies of your tests! Make nice with the staff and get the copies before you leave every time you have anything. I ask the lab to send me a copy but that is about 25% now.
If you start at 12:45 you end at 12:45! it is a time thing! Discard the first void and go from there. I wait a day before turning in so my specimen gets nice and cold in the fridge now.
If you start at 12:45 you end at 12:45! it is a time thing! Discard the first void and go from there. I wait a day before turning in so my specimen gets nice and cold in the fridge now.
thanks lady,, yeah I have no idea the range they are using and I have been staying up till 3 or 4 then waking at 1 or 2 in the afternoon,,, i heard that can make a big difference as well,, i had my morning pee at 12 45 in the afternoon the day I turned in the specimen so,,,,, lol,,,,,I knew this wouldnt be an easy road,,, thanks for your input was needed greatly!!!!
Some labs/methods have a 34 cut off so you may have been almost there - or the cut-off is 50 but that test is oddly less specific (the other test is better)...
As for the point in time vs the average test... there can be lots of reasons to be high in one and not in the other. Sometimes it is just hard to hit a point in time test. As for the averages, I used to mess mine up as I was high at night, but low during the day - ergo - my average was just FINE but I was sicker than a dog... also medications can interfere with free type tests (urine and saliva). Also if you have a high cortisol binding globulin, you just may have less free cortisol around even though you may be sick. Lab error - if you had more than one jug and the lab tech did not mix them all and them take the sample - error. Did not keep cold - error...
Is that enough?
As for the point in time vs the average test... there can be lots of reasons to be high in one and not in the other. Sometimes it is just hard to hit a point in time test. As for the averages, I used to mess mine up as I was high at night, but low during the day - ergo - my average was just FINE but I was sicker than a dog... also medications can interfere with free type tests (urine and saliva). Also if you have a high cortisol binding globulin, you just may have less free cortisol around even though you may be sick. Lab error - if you had more than one jug and the lab tech did not mix them all and them take the sample - error. Did not keep cold - error...
Is that enough?
ok,, how is it that my 24 hour urine test was normal but I still have high morning blood cortisol????? so confused!
ok,, got my 24 hour free urine results,,,,I think they are normal,, the girlon the phone said I had a 33.1 level,,, i have no idea what the ranges where lolI ll know more at my appointment I guess// any info you could give would be great,, thanks lady ;... I keep thinking she read my am blood levels though,,, ugh
Yup - keep it COLD...
The creatinine is tested to see if you over sample - as in collect more than 24 hours. However some of us have high creatinine (I was told, rudely, that the doc expected since I was a big girl) so it is not perfect - but that is the reason.
If you can't get to the lab super soon, you can even freeze it but it has to be thawed before you take it to the lab - thaw in the fridge. The peecicle can never be warmed.
The creatinine is tested to see if you over sample - as in collect more than 24 hours. However some of us have high creatinine (I was told, rudely, that the doc expected since I was a big girl) so it is not perfect - but that is the reason.
If you can't get to the lab super soon, you can even freeze it but it has to be thawed before you take it to the lab - thaw in the fridge. The peecicle can never be warmed.
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She was probably reading the levels for normal cortisol. When you get the test the lab does not know you had dex so the ranges are still for AM cortisol - so for that, you are, gee, really low - but for the test - you almost made it - again, showing, she has no idea how to administer the test.
Find another doctor.