Is this still Stage 4 what is Nottingham Score-Grade III: 8-9 points? How many possible points are there: This is from my pathology report
Lymph Node Sampling: Axillary dissection
Specimen Size: Greatest dimension: 7.6 cm
Additional dimensions: 5.2 x 3.4 com
Tumor Site: Upper outer quadrant
Size of Invasive Component: Greatest dimension 0.4 cm
Histologic Grade: Nottingham Histologic Score-Tubule formation: Minimal less than 10%
Difinition of Nottingham Score-Grade III:8-9 points
pN1a: Metastasis in 1 to 3 axillary lymph nodes (at least 1 tumor deposit greater than 2.0 mm)
Number of nodes examined: 15
Number of nodes involved: 1
pMX: Distant metastasis cannot be assessed
Margins: Margins uninvolved by invasive carcinoma
Margins uninvolved by invasive carcinoma - Distance from closest margin:0.7 mm
I had a score of 9 with a 5cm tumor removed, 1 node involved....stage 3. Stage 4 is metastatic cancer involved in the system, not just a tumor and a node. But to make sure, check out a book on breast cancer that has the EXACT defintitions. Sorry, I've already given mine away, otherwise I'd give more specifics.
Nottingham Score is a prognostic scoring tool.
Breast cancer is usually staged based on TNM staging chart.
Any biopsy report should mention the size of the tumour, cut section appearance of the specimen. The specimen should be carefully examined forthe clearance of the margins, the differentiation of the cells, the mitotic index of the cancer cells. In addition to this, hormonal markers analysis is also done.
When you say breast cancer of stage 4 it means advanced stage of breast cancer.
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