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hi wow !!! almost the same as me , mine had spread to chest wall and 18 positive lymph nodes. i was dx in oct 2005, i am doing GREAT! a walking miracle. this is a very agressive treatment so yes it is good, and i also had radiation after chemo,a hysterectomy and a port in neck for chemo.the doxorubin is a definate hair loss. take care pleaase keep me posted and may god be with ur wife.xo j