Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum. ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
Breast Cancer (Expert Forum)
4 AC is enough for an adjuvant chemotherapy after lumbectomy ?
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.
4 AC is enough for an adjuvant chemotherapy after lumbectomy ?
by samu, Aug 13, 2001 12:00AM
I am 59 years old, 5 years postmenopausal lady. I was on HRT for
5 years. On June 20, 2001, I had a lumbectomy and axillar lenphadenectomy. 1,5 x 1,5 x 2 cm. tumour was removed with 15 axillary nodes. Surgical margins were clear and 1(one) lenf node(in level 1) was involved with an invasion to its own capsule. Pathology is invasive ductal carcinoma, histologic grade 2. ER and PR were positive. Her2 was also slightly positive. My own oncologist advised 4 AC + Radiotheraphy + Tamoxiphene.
But I have heard that some doctors add 4 Taxol, even with Herceptine as an adjuvant chemotheraphy after 4 AC + RT.
Is that a trial procedure or a standart regime in some medical schools? Is that worth taking Taxol and Herceptine after 4 AC + RT in my conditions in my age? I have not any other systemic disorders like heart disease, Hypertension, Diabetes, or Obesity.
Thank you.
5 years. On June 20, 2001, I had a lumbectomy and axillar lenphadenectomy. 1,5 x 1,5 x 2 cm. tumour was removed with 15 axillary nodes. Surgical margins were clear and 1(one) lenf node(in level 1) was involved with an invasion to its own capsule. Pathology is invasive ductal carcinoma, histologic grade 2. ER and PR were positive. Her2 was also slightly positive. My own oncologist advised 4 AC + Radiotheraphy + Tamoxiphene.
But I have heard that some doctors add 4 Taxol, even with Herceptine as an adjuvant chemotheraphy after 4 AC + RT.
Is that a trial procedure or a standart regime in some medical schools? Is that worth taking Taxol and Herceptine after 4 AC + RT in my conditions in my age? I have not any other systemic disorders like heart disease, Hypertension, Diabetes, or Obesity.
Thank you.
Doctor's Answer
by CCF-RN,MSN-JS, Aug 14, 2001 12:00AM
Dear Samu, Currently Taxol is an approved chemotherapy for use as treatment of metastatic breast cancer. It’s use as adjuvant therapy is still in clinical trials. Adjuvant therapy means treatment given after surgery to try to prevent or minimize the growth of microscopic deposits of tumor cells that might grow into a recurrent tumor.
The question being asked in some of the trials is - by adding Taxol after the A/C does this improve the overall outcome? Meaning, what we’d like to know is, if we are giving a drug that has the potential to cause more side effects, and delaying radiation treatment until that drug is given, will this benefit the patient in the long run? Until the data from the trials are evaluated we don’t know whether the addition of Taxol has merit in the adjuvant setting.
The question being asked in some of the trials is - by adding Taxol after the A/C does this improve the overall outcome? Meaning, what we’d like to know is, if we are giving a drug that has the potential to cause more side effects, and delaying radiation treatment until that drug is given, will this benefit the patient in the long run? Until the data from the trials are evaluated we don’t know whether the addition of Taxol has merit in the adjuvant setting.
Member Comments (3)
by Philip1815, Dec 10, 2001 12:00AM
test
by Philip1815, Dec 11, 2001 12:00AM
test2
