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Unless your friend has been previously diagnosed with breast cancer I can't see why this would be even considered at this point. If the areas of concern are pain and the results showed uptake in the spine area I would be thinking something related to bone rather than breast cancer. Bone Scan will pick up "everything" .... mine showed uptake in the jaw where I had an abscessed tooth several years before. With neg. Mammo and Ultrasound it's highly unlikely that there is a breast issue here. Keep in mind that everything I have said is based on the fact that there was no previous diagnosis of breast cancer !!!
I am a nurse and the two radiologists I spoke to right away said it sounds like metastisis (and this is with no cancer history) . What concerned me was that there was uptake in quite a few spotsBirthmarks - pigmented Liver spots Measles, koplik spots - close-up Mongolian blue spots. I am also a bit worried because a patient of my sister's had a negative mammogram and ultrasound and had an MRi that came back with breast cancer in both breasts and metastisis.
As I'm sure you are aware, this would be quite a rare thing to be diagnosed by bone scan with no previous symptoms or testing. Every type of imagery I have for things that have nothing to do with my previous cancer diagnosis always come back with "metastises" as the first opinion listed. None have been related in any way to cancer though. Please keep me posted as to the results of the surgical consult; I'm very interested in the outcome. Thanks .....