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Bone metastasis

Bone metastasis

My aunt was diagnosed with breast cancer one and a half year ago and has undergone treatment (radiotherapy, surgery - radical mastectomy, chemotherapy (FEM and Tamoxifen. Aredia (Bondronat), Farmarubicin Ftoruracil, Endoxan, Tamoxifen has been replaced with Arimedex. Aredia (Bondronat), Taxol, Farmarubicin. Zoladex
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Dear Natia, The goal of treatment for metastatic breast cancer is control of the disease and symptoms.  Treatment can be approached from many angles.  One method is through the use of various chemotherapy medications, such as Taxol, or combinations that are given for earlier stage disease (Cytoxan, methotrexate or adriamycin/epirubicin, 5-fluorouracil).  Hormonal manipulation may be especially useful for those with predominately bone metastasis.  Aromatase inhibitors such as Arimidex are also used.  The monoclonal antibody Herceptin, is also used in patients whose tumors overexpress HER2 protein receptors.  The use of these treatments and the order and/or combinations in which they are used varies.

Bone metastases secrete substances that can cause cells, called osteoclasts, to dissolve or
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