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Breast Cancer  (Expert Forum)
 | 
Calcifications & Surgical Biopsy
Answered by
Cleveland Clinic - breast cancer
Cleveland - OH
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.

Calcifications & Surgical Biopsy

by Soldier37, Jun 23, 2007 12:00AM
I am 37yo.  I had my 1st mamo. at 35.  Calcifications were found on left breast, 2" up and left of my nipple.  Repeated mamo. every 6 mos.  This time they found growth on original calcifications and new microcalcifications.  Did magnified mamo. at hospital.  New clusters run from larger calcifications down to behind my nipple.  Radiologist said I can't have a needle biopsy because of position so I have an appointment for surgical consultation.  The only thing I know from last mamo. is BIRAD 4.  Should I be concerned this is cancer?  Everything I read says only about 1 in 4-5 is malignant.  I have history of other cancers in family but not breast (that I know of).  I used to smoke heavily but not for about a year.  I know you can't diagnose.  I just want to be prepared if cancer is more than a slim chance.

by Cleveland Clinic, Jun 25, 2007 12:00AM
Dear Soldier37, A BIRADS rating of a mammogram helps to categorize a finding in terms of how suspicious an abnormality looks, and whether further evaluation of an area is recommended. A BIRADS rating of 4 would be described as a suspicious looking abnormality, not characteristic but has a reasonable probability of malignancy and a biopsy should be considered.  To know for sure what this area of concern is, a biopsy would need to be done.

Member Comments (31)

by lizziecee, Jun 23, 2007 12:00AM
To: soldier37
Hi soldier - as far as I am aware, a BIRAD score of 4 means highly suspicious of malignancy. You might try googling "BIRAD scores" for further information.
I would guess you need to see a breast cancer surgeon for further testing.
Good luck
Liz

by japdip, Jun 23, 2007 12:00AM
I disagree with the above post in that a BIRAD 5 is highly suggestive of malignancy but a score of 4 is 25 - 50% might be due to something OTHER than cancer. The surgical biopsy is not such a big deal .... a very small incision (1-2 in.) Evreything will be explained by your surgeon and don't forget to ASK, ASK, ASK until you are satisfied. Let NO question go unanswered. Best of Luck to you, stay cool and take it one step at a time.

by Montana girl 06, Jun 23, 2007 12:00AM
Yes, Birad 4 is suspicious, but with calcifications around 80% of biopsies tend to be benign. I've had 2 benign biopsies for calcifications myself and now they just follow mine with a mammo every 6 months. Mine also increase over the years until they get to the point the radiologist recommends a biopsy. I know how upsetting it is to get this news, but there is a great chance they will be benign. It's still best to get the biopsy to set your mind at rest.

by Soldier37, Jun 23, 2007 12:00AM
Thanks for the input!  My niece (by marriage) is in the middle of chemo.  I guess I'm just nervous because someone close to me has been recently diagnosed.  I wish I had the radiology report.  I'm going to call on Monday to see if I can get a copy before I meet with the surgeon on Tuesday.  I want to be able to ask as many questions as possible.  The nurse was very vague when she told me I needed to follow-up with biopsy.  The only information I came away with was just what I wrote in my first post.  I'm glad that things seem to be moving along though.  I've read so many posts about having to wait up to weeks between appointments before you get any answers.  My mammogram was Thursday and I get to see the surgeon on Tuesday.  I'll let you know how things turn out.

by lizziecee, Jun 24, 2007 12:00AM
To: japdip
I  do unfortunately take exception to your last post. A BIRAD score of 4 is possibly malignant - criteria is 3 or 4 malignant findings. Why don't you research it, as I have done? We as breast cancer survivors, owe it to the newly diagnosed, to post here with the very best information we have.
I am very disappointed with your post - I do the best research I can, having breast cancer, and I do not like people like you coming on here with inaccurate information when people newly diagnosed are floundering for information.

by japdip, Jun 24, 2007 12:00AM
PLEASE READ ...... this is one of the many replies by the Professional who routinely answers questions on this board. My reply was a professional one but in no way to be thought of as that. This was copied from a previous post.

A BIRAD Category 4 means that there is a suspicious abnormality. Most category 4 abnormalities are benign but may require biopsy since this category can be malignant in 25-50% of cases. You should discuss with your radiologist or surgeon when it is safe to breast feed from that breast again.

I am sorry you objected to my previous post but please try not to advise patients if your information isn't correct. What you read was that 3 or 4 out of a certain number of cases were found to be malignant with a score of 4 ..... NOT 3 or 4 indicates malignancy.

To the original poster .. the Professional from the Cleveland Clinic will answer your questions on Monday. Hang in there and take everything with a grain of salt .....

by Montana girl 06, Jun 24, 2007 12:00AM
To: liziecee
You have been helpful to many at this site but according to my research I have to agree with Japdip that your first post in this thread was incorrect. You stated BIRAD 4 is highly suspicious of malignancy. BIRAD 4 is "suspicious" and using the word "highly" belongs to BIRAD 5 - "Highly suggestive of malignancy" as I quote directly from my radiology report. To me the words "highly suspicious" are very alarming and that's why they are used for BIRAD 5.

This is supposed to be a support forum and when one person attacks another it destroys the comradery at this site. It seems we should be able to express differences and corrections without attacking.

by Avidhiker, Jun 25, 2007 12:00AM
I am a breast cancer survivor.  In April of 2006, my mammo was given a BIRAD of 4 which I know for a fact means "suspicious abnormality".  A biopsy was recommended.  I had microcalcifications spread out over too large an area for any needle biopsy.  I had an excisional biopsy and unfortunately mine turned out to be malignant.  At the time, I asked my surgeon the chances of this happening and he advised that 15% turn out to be malignant.  This, of course, means that 85% of the time it is not.  Since April of 2006, perhaps these percentages have fallen or risen.  My surgeon has 33+ years of breast surgery and diagnosing and treating breast diseases.  I believe what he tells me.  

By the way, I also know for a fact that a BIRAD 5 rating is "highly suggestive of malignancy".  A BIRAD 6 is after the biopsy and means "known biopsy-proven malignant".

To soldier37:  GO ASAP FOR YOUR BIOPSY!  If it is cancer, it will be EARLY and that is the most important issue.  Good luck.

by blkw, Jun 25, 2007 12:00AM
You mention the percentage of biopsy of calificatioin clusters that are cancer vs. benign. Does this percentage vary by age? I'm 37 and having a calification cluster biop this Thursday (my mother also had breast cancer), I'm wondering if the percentage of non-cancer findings is higher over 50/under 50 or over 40/under 40. Thanks,

by lizziecee, Jun 25, 2007 12:00AM
To: all you lovely people on here....
I truly apologise if I said anything incorrect.... I would not purposely mislead anyone with this awful disease.  When I had my 3rd mammo at 58 yrs, at a travelling van in the isolated place I live, I had a BIRADS 4 - then I was recalled to a breast care centre where my surgeon said that a BIRAD 4 was highly suspicious of malignancy - perhaps by the mammo which I eventually saw, that showed a black mass, which was spiculated. I may be in a minority of BIRADS stage 4. that was dx with breast cancer,  but at least it was picked up. I just wanted to detail my own experience and let Soldier realise how important the score is/was.

I eventually was dx with a 2 cm invasive tumour and spread to the lymph nodes
I apologise to anyone I upset by my post.
Liz.

by japdip, Jun 25, 2007 12:00AM
To: bikw
Hi .... I believe there isn't a difference due to the age of the patient. If you would like an answer from the Cleveland Clinic Professional you should ask your question as a post rather than just a comment. They never read the comments; just the original post. I know it's difficult to get on the forum but if you try at different times of the day (and even late at night) you will eventually be able to post. They reset at different times each day to give those in different time zones an opportunity to post.

by boninclyde, Jun 25, 2007 12:00AM
Well I guess I'll butt in. I have been scolded and I have scolded some on this site. I had to learn patience. It is most of the time a mis-interpretation and we don't mean to harm anyone. We only try to help. We appreciate being corrected. We are all here to learn. Lizzie has been a great help on here and has helped alot of people. Thank you all who post so much for taking your time to help.

by Soldier37, Jun 25, 2007 12:00AM
Thanks to everyone for all the info.  I got my report today but it was only one page and not very descriptive.  Most of the information I got from the nurse after my appointment wasn't even on it.  Do they do a summary report or something?  I wanted to see it so I could ask questions tomorrow.  My BIRAD rating wasn't even on it nor were any of the measurements of the clusters.  One thing I did see is that if I have a family history, the radiologist thinks this could be more of an indication of malignancy.  The only problem is that my mom died at 52 with colon cancer.  She had something in her breast but since she refused further treatment for the colon cancer, she never did anything about the spot on her breast.  I have no idea whether it could have been something or not.  I guess I'll see tomorrow what the surgeon thinks.

by Montana girl 06, Jun 26, 2007 12:00AM
To: Soldier37
I hope all goes well. Keep us posted.

by blkw, Jun 26, 2007 12:00AM
To: japdip
Thanks for the advice and reply. I'm new here. I've been trying to do some of my own research (which is probably making me more nervous instead of helping) but can't find the answer to this question.  I got it posted this morning.
Thanks again and best regards to you,
-blk

by Soldier37, Jun 26, 2007 12:00AM
Hi everyone!  I had my consultation with the surgeon today.  I feel so much better!  I'm having a stereotactic biopsy next Tuesday.  He gave me the same percentages as most of you - "...85% of cases similar to your circumstances are benign".  I am also glad I don't have to have an open biopsy.  Hopefully, I'll know for sure by the end of next week.  I really think everything is going to be alright.  I'll pass on the good news to you when I get it.  Hope you all are doing well. Thanks for all the support.

-Soldier

by Montana girl 06, Jun 27, 2007 12:00AM
To: Soldier
Thanks for keeping us posted. I'm glad your biopsy is scheduled soon so you can get some answers. I hope you join the benign group.

by lasimon, Jun 28, 2007 12:00AM
I went for my mammogram a few weeks ago and I was asked to come back for some additional pictures for my right breast- ( I have family history of breast cancer also- Mother at 37 and an aunt also ) When I had the additional pictures done the radiologist said that everything is fine but they want to have me come back in 6 months for another mammogram.  After this I received a letter in the mail from the place where my Mammogram was done and they used the term you "PROBABLY" dont have cancer but you need to come back in 6 months for a recheck- I called my Dr who was to get the information and wanted to understand what the word"probably" meant???  I could have cancer or I don't?? really felt uneasy about the letter just leaving it as is.  My Dr. Then called back and sent a referral for and MRI to be done.  Is this letter common for woman to get with high risk of cancer history in family?  Just curious if I am overreacting.....

Thanks in advance for any advice!!!

by Montana girl 06, Jun 29, 2007 12:00AM
To: lasimon
I recommend you get an actual copy of the radiology report so you have as much info as possible. It would be a good idea to ask for a copy after every mammogram so YOU can follow your reports and not just leave it in the doctor's hands. It is fairly common for women (whether they have family history or not) to get a notice that they should come back in 6 months to check an area that is probably benign, but since they're not certain they want to keep an eye on it. It's also fairly common for radiologists to follow somewhat suspicious findings in the breast and not even let the patient know! Since they said come back in 6 months I'm guessing the radiologist gave it a BIRADS 3 rating on a scale of 1-5. That means it's highly unlikely it will be cancer. But, with your family history it's great that your doctor is moving forward with an MRI. I just want you to know that MRI's have a fair number of FALSE positives. I really hope you get some answers, because I know how scary it is to just wait and wonder if you have cancer. I hope all goes well with your MRI.

by lasimon, Jun 30, 2007 12:00AM
To: Montana Girl 06
Thanks Montana girl.  I'm praying that everything goes good also- my test is on Friday the 13th-:(  but hey- never had anything bad happen before on this date so I hope that the trend continues!

Have a great 4th of July!!!

by stresscase123, Jun 30, 2007 12:00AM
Get it checked out for peace of mind, if there is *any* question, IMO.

For the record, I had my baseline mammo and was given a BiRADS score of 3 for calcifications.  The radioloigst suggested I have a biopsy, since we had no history on the calcs, but also told me waiting 6 months was an option, since it was highly likely to be benign.  I went ahead with the biopsy, and lo and behold was diagnosed w/DCIS!

Regardless of BiRADS, if the techology exists to rule something in or out, we should take advantage of it.  The benefits of early diagnosis far outweigh the inconvenience/risks of an unnecessary biopsy, IMO!

by Montana girl 06, Jul 01, 2007 12:00AM
To: stresscase123
How are you doing? Did you need more treatment after your surgery, or did they feel they removed everything? Haven't heard from you in awhile and just wonder how you're doing.

by Bay area girl, Jul 16, 2007 12:00AM
To: Montana girl 6/2007
I would like some comments about this. I am 53 with this being my first call back on a mamogram (mammogram).   I have a core biopsy scheduled 2 days from now on one of 2 similar cluster amorphic microcalcifications on the right breast.  I got a birad 4 classifications but the dictor said in the report that they were faint and hard to see and that is why the biopsy.  I insisted that both clusters be biopsied and removed but the doctor said emphatically that that would be removing too much tissue and if I wanted both removed I should go to a breast surgeon.  I read every forum comment on core biopsies and I noticed that many had more than one cluster biopsied.  I am going ahead with the initial biopsy but I am of couse concerned and frightened.  Any  comments?

by Montana girl 06, Jul 16, 2007 12:00AM
To: Bay area girl
First, you need to know that I am not a medical professional and talk only from my personal experiences and from what I've read.

I wonder if your clusters of microcalcs are too far apart to biopsy in 1 proceedure. It's also possible that they are too deep and they feel they might not be successful.  This is just a guess.  With my last stereotactic biopsy I had several clusters near enough that they got a good sampling of the area. But, my clusters were not removed entirely.

At your biopsy I would ask why they chose that particular cluster of microcalcs to biopsy and why not the other, and why they felt a biopsy of only 1 cluster would be sufficient. Also, ask if they removed the entire cluster or just sampled it.

My experience with surgeons is that they are often not eager to remove a large area unless they really feel core biopsy is not adequate. I've had 2 different surgeons choose not to remove the large area recommended by the radiologist because it would remove about 1/3 of my breast and become a major surgery.

Please remember that most microcalcifications (even those biopsied) are benign. I wish you well with your biopsy.

by brittnat, Jul 17, 2007 12:00AM
To: soldier37
What were your results from your biopsy?  iam new to all of this, and have a biopsy (mammotone ) tomorrow.

by mimizerr, Aug 05, 2007 07:59PM
To: soldier37
How did the sterotatic biopsy go?  I had one last August and it was so painful I saw stars during the procedure.   I had a cluster of cacifications.  The mamo revealed the calcifications were gone after the procedure.  Last month I had a mamo and all was clear.  Last week my breast hurt and I found a hard lump.  I think it is left over from the stereotatic biopsy.  Next time I will just have the surgery.
What are your thoughts on the stereotatic biopsy?

by xander1218, Aug 10, 2007 10:26PM
I have microcalcifications, BIRAD 4,  and scheduled in a few weeks to see a Surgeon for a  Biopsy Consultation.  Over the phone, the Nurse from the Surgeon's Office, told me I will have a Stereotatic Biopsy.  However, the Surgeon hasn't physicaaly seen me yet and my glorious 32AA breasts.  After doing more research, I just learned that because of my size (or lack there of) I will have to have an Open Surgical Biopsy.   Is this true?  Is this the only Biopsy choice for very small breasted women?

by Jackieone, Aug 11, 2007 07:14AM
Hi everyone. Just wanted to thank all of you for the fine information. I'm 51 and will have a surgical biopsy on August 21. I have a 2cm area of calcification. I saw the surgeon Thursday and he didn't feel any abnormalities which is good. I also had a softball hit me last year in the same area so I'm 90% sure that its not cancer but better safe than sorry. The surgeon told me to get and wear a loss fitting good support bra. I've never heard of a support bra being loose fitting before. I plan to go the the local Perfect Fit store and see if they can help me with that. He says I'll need to sleep in if for a few days after the surgery. Anyway, I just wanted to let you know that this forum helped me with knowing what questions to ask and calmed my fears.

Thanks,
Jackieone

by boninclyde, Aug 11, 2007 09:04AM
Hello ladies. Just wanted to suggest you start a new post further up on like page one. I think you are 3/4 pages back and sometimes the other ladies here don't read this far back. Jump up to page 1 with us so we can all chime in and try to help.

by Montana girl 06, Aug 11, 2007 10:42PM
xander - I'd try to call the nurse and talk to her about your research. I hadn't heard they couldn't do stereotactics on small breasts, but there's a lot I don't know.

Jackieone - I wore a tight fitting sports bra after my stereotactic and it worked fine. When I went back to work the next day I put my regular bra over my sports bra (to give more shape since most sports bras flatten me) and slipped a small ice pack in between the two bras. Sorry to hear about your calcs. Hope all turns out well.

by misawa47, Sep 02, 2008 09:20PM
A related discussion, Stereotactic Biopsy yielded no Calcifications was started.
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