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Breast Cancer (Expert Forum)
Chemo recommendation
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.
Chemo recommendation
by cnsal, May 16, 2001 12:00AM
I am 43 years old with no family history of breast cancer.
My path report reads:
- 0.8cm Grade I invasive ductal carcinoma (from surgical biopsy)
- 0.6cm Grade I residual invasive ductal carcinoma, surgical margins free (after mastectomy).
- Extensive DCIS, 5.2cm.
- ER/PR positive (2+, 90%)
- Her-2/neu negative
- Ki-67 Staining shows 5-10% proliferation rate
- no definite angiolymphatic invasion
- 8 lymph nodes free of carcinoma (0/8 positive)
I had modified radical mastectomy done in mid-April and definitely needs to decide if chemo is needed. 2 Oncologists give different opinion. Both agress that the tumor size is 1.4cm total. One suggests 4 cycles of A/C while another one doesn't recommend any chemo. As expected, both recommends tamoxifen for 5 years.
What will be your recommendation ? What is my chance of my recurrence with or without chemo ?
Thanks a lot.
CNSAL.
Doctor's Answer
by CCF-RN,MSN-JS, May 17, 2001 12:00AM
According to the 2000 National Institute of Health Consensus Conference on Adjuvant Therapy for Breast Cancer. Adjuvant chemotherapy (treatment given after surgery to try to prevent or minimize the growth of microscopic deposits of tumor cells that might grow into a recurrent tumor) is recommended for the majority of women with primary breast cancers that are greater than 1 cm in diameter. This is independent of nodal, menopausal or hormone receptor status.
