Chemo vs Oopherectomy

I am 40 Y, had a simple mastectomy and was staged as Stage III with extensive DCIS and ductal invasive tumor 5cm, ER+, PR+, Her2+, micrometastes (2.5mm)in the one sentinel lymph node taken.
1) What do questions should I explore in considering oopherectomy instead of chemotherapy - to deal with the underlying risk of recurrence without the side effects.  (I am also doing Chinese medicine complementary treatments, diet and exercise).
2) What are the most recent findings on using aromatase inhibitors instead of tamoxifen on ER+HER+ for prevention of recurrence in premenopausal women.  Can you provide any research citations that might illuminate these issues?

[CCF-RN,MSN-rf]

Dear carlota:  1) Oopherectomy is not an alternative to chemotherapy.  It is sometimes considered to be a more aggressive approach to blocking estrogen (e.g. in addition to tamoxifen).  LHRH agonists (such as Lupron or Zoladex) can be used to chemically do the same thing as an oopherectomy.  These methods are used in addition to chemotherapy and address the ER/PR status.  2) Aromatase inhibitors are not indicated in premenopausal women.  The research to date has been on post menopausal women.

[surgeon]

to opt out of chemotherapy for a stage III tumor would be to go in an unconventional direction: it's well-established and accepted as necessary treatment in this circumstance. That's not to say hormone therapy alone would definitly be inadequate, but for large numbers of women, there'd be more cures in those who took chemo: and probably hormone therapy after, as well. We can't predict on an individual basis. So your choice would be based on a decision to decline chemo as recommeded. If you were to do so, it would definitly be a good idea at least to have hormone therapy. Oopherectomy is not the primary way of doing so: typically medications are used as first treatment. Whether oopherectomy is as effective as hormone blocking medications is probably unknown. But the drugs may well do more than just prevent estrogen from interacting with tumor cells; in other words, they may have an effect over and above that of eliminating estrogen, which would occur from oopherectomy alone.