Dear the_deceived: Side effects of chemotherapy occur because chemotherapy damages rapidly dividing cells such as the blood cells, gastrointestinal tract cells and the hair follicles. In most cases, the hair just falls out (usually in clumps) but not in a painful or bloody way. It comes out in the shower, while combing the hair and often people wake up with large amounts of hair on the pillow. Chemotherapy does not burn the scalp. The skin on the scalp may be dry or itchy. Not all chemotherapy causes hair loss. Hair generally grows in uniformly once chemotherapy is completed.