I am 40 years old and had a hysterectomy when I was 22 years old. I've been on and off of Premarin and Estradial since that time. From the beginning I was warned by my physician of the possiblity of breast cancer associated with estrogen, especially since I was so young when I started taking it. During an annual visit, the nurse practicioner felt a lump in my breast and scheduled me for a digital mammogram . After reviewing the images, the radiologist suggested an ultrasound. My right breast showed macrocalcifiations & microcalcifications and suggested that I wait at least 6 months and repeat a mammogram to watch for changes. Is this normal? I am cosidering a second opinon. I am very concerned. Please help.