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Breast Cancer (Expert Forum)
ER in premenopausal woman
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.
Doctor's Answer
by CCF-RN,MSN-rf, Feb 25, 2002 12:00AM
Dear yhaskel: Actually, for the treatment of breast cancer, it makes no difference whether a woman is premenopausal or postmenopausal. What matters is that the tumor is estrogen receptor positive. Tamoxifen is effective in estrogen receptor positive tumors - regardless of menopausal status. An article discussing this was published in The Lancet in 1998. However, you may read a nicely written summary in Dr. Susan Love's Breast Book, published 2000, pages 391-393.
If you are referring to the use of tamoxifen for prevention in high risk women who have not had breast cancer, then it is used in postmenopausal women only.
If you are referring to the use of tamoxifen for prevention in high risk women who have not had breast cancer, then it is used in postmenopausal women only.
