HER 2

Woul d like to know the significance of the HER 2 results In pathology reports.  I was HER2 - Positive 2+ and also oestrogen and progesterone positive.  I am on Tamoxifen and Herceptin was never mentioned, yet I have read various comments that HER positive tumours need Herceptin - could you please clear this up.  My tumour  a 5mm invasive stage 1 with associated DCIS which was intermediate.  Clear margins.  Many thanks.

[Irishgal2]

I am ER and PR positive but Her 2 negative.  However the initial pathology result had my Her2 status at 2+, which is middle of the road.  Because of this the test was also done at an alternative hospital and got a reading of 1+ (which is negative).  The most accurate test is called a FISH test but it is only done in a number of hospitals.  It does take a little time, but you get a definite and accurate answer.  The result of the FISH test for me was negative.  I suggest that you ask your doctor for a definite negative or positive Her2 result and if you happen to be positive, then yes you most definitely should be asking your doctor about Herceptin.

Good luck.

[Jaydew]

Thanks for your reply -  I have heard of the FISH test but have been told by the Dr. not to worry about HER status.  Does leave me with niggling worries everytime I hear people say that HER positive requires Herceptin.  Will ask again when next due for a follow-up appointment.