BREAST CANCER EXPERT FORUM
Mode of Inheritance

Mode of Inheritance

I am a Pre-Med student wondering what the mode of inheritance is for Breast Cancer?  From research that I have done, it appears that it is a sex-limited autosomal dominant gene, but that doesn't make sense to me.  Please help!
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Dear ChristineCMD:  I have spoken with our genetic counselors.  Indeed the BRCA-1 and BRCA-2 are autosomal dominant genes.  However, they are not x-linked.  Whether or not a person develops breast cancer is more related to gender, female that is.  Although, males with the BRCA-2 gene have a 10-20% chance of developing breast cancer.
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