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Breast Cancer  (Expert Forum)
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Mode of Inheritance
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.

Mode of Inheritance

by ChristineCMD, Oct 30, 2001 12:00AM
I am a Pre-Med student wondering what the mode of inheritance is for Breast Cancer?  From research that I have done, it appears that it is a sex-limited autosomal dominant gene, but that doesn't make sense to me.  Please help!

by CCF-RN,MSN-rf, Oct 30, 2001 12:00AM
Dear ChristineCMD:  I have spoken with our genetic counselors.  Indeed the BRCA-1 and BRCA-2 are autosomal dominant genes.  However, they are not x-linked.  Whether or not a person develops breast cancer is more related to gender, female that is.  Although, males with the BRCA-2 gene have a 10-20% chance of developing breast cancer.
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