Aa
A
A
Close
Avatar_universal
Nottingham Scale Question
What's the relationship between the mitotic rate on the Nottingham Scale and the doubling rate of a breast cancer cell? My score was a 1.
Discussion is closed
Cancel
2 Answers
Page 1 of 1
25201_tn?1255584436
If you haven't already I would prefer that you post this question on the "Expert" Breast Cancer Forum where the posts are answered by the Cleveland Clinic Physicians   OR  perhaps you might ask your Oncologist.   Thanks .......
Discussion is closed
Cancel
962875_tn?1314213636
As you may be aware, the Nottingham Scale and the Bloom-Richardson Scale are two similar  scales commonly used to determine the histopathologic grade of a tumor.  They produce a tumor grade by considering what the cells look like, how fast growing they are dividing, etc.

The Bloom-Ricardson Scale, for example,  adds together  3 scores given in regard to mitotic rate (your score of 1 is low, or good!), nuclear grade, and cellular differentiation, to come up with a total score, which then determines the final Grade.

Both scales lead to an overall Grade of 1 (not very aggressive), 2 (medium aggressiveness) or 3 (highly aggressive).  The Grade of the BC helps (along with several other factors) in the determination of how aggressively the BC needs to be treated.

Best wishes...
Discussion is closed
Cancel
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Breast Cancer Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1443740527
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top Breast Cancer Answerers
25201_tn?1255584436
Blank
587083_tn?1327123862
Blank
961574_tn?1449149056
Blank
Lancaster, OH