Dear Cheryl: Without reviewing the x-ray and bone scan, it is impossible for us to make any meaningful interpretation of what this may mean. If the bone scan is not definitive, the PET scan may help to clarify the likelihood of whether or not this may be metastasis. The results of the PET scan may also help to determine the next steps. Your oncologist may be better able, having reviewed the scans, to discuss the possible explanations for the abnormal activity.