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Breast Cancer (Expert Forum)
Pathology Report from Lumpectomy
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.
Pathology Report from Lumpectomy
by Bet63, Mar 20, 2003 12:00AM
I had a large lumectomy due to cluster microcalcifications and these findings were noted on my patholgy report;
1st speciman: densely fibrotic and hyalinized breast stroma. Large and small cysts present. Apocrine metaplasia noted.
2nd speciman: hyalinized dense fibrous stroma with large and small cysts together with foci of apocrine metaplasia.
Can you explain to me what these terms mean? I know there is no malignancy here but am confused and concerned about apocrine metaplasia and the hyalinized tissue. Is this something that needs to be watched? Is this a marker for future BC? My surgeon said he needs me to have another mammo 2 months post-op.
I am 39 with a strong family history of BC. (mom 42 when DX and cousin 32 and elderly grandmother with inflammatory BC) I have fibrocystic breasts and have had 2 previous lumpectomies about 12 years ago, both fibroadenoma. I've been having regular mammo's since I was in my 20's and have never had microcalcifications before.
Thank you so much for any info you can give me. This is a wonderul informative site.
1st speciman: densely fibrotic and hyalinized breast stroma. Large and small cysts present. Apocrine metaplasia noted.
2nd speciman: hyalinized dense fibrous stroma with large and small cysts together with foci of apocrine metaplasia.
Can you explain to me what these terms mean? I know there is no malignancy here but am confused and concerned about apocrine metaplasia and the hyalinized tissue. Is this something that needs to be watched? Is this a marker for future BC? My surgeon said he needs me to have another mammo 2 months post-op.
I am 39 with a strong family history of BC. (mom 42 when DX and cousin 32 and elderly grandmother with inflammatory BC) I have fibrocystic breasts and have had 2 previous lumpectomies about 12 years ago, both fibroadenoma. I've been having regular mammo's since I was in my 20's and have never had microcalcifications before.
Thank you so much for any info you can give me. This is a wonderul informative site.
Doctor's Answer
by CCF-RN,MSN-rf, Mar 21, 2003 12:00AM
Dear bet63: Apocrine metaplasia means that some mature tissue has changes that are not normal. This is commonly seen in fibrocystic breast disease. Hyalinized tissue is only describing the tissue. Bottom line is that there is no evidence of malignancy or premalignancy. These are not premalignant changes.
Thanks again!
Bet