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Stage

Pathologic stage: PTIC(m) pno (i-) pmx
What does this mean?
tumor 1: invasive ductal carcinoma nottingham grade 3 of 3 no lymphocascular invasion is identifed.
tumor 2 invasive carcinoma consisten with metaplastic carcinoma, matrix producing type: nottingham grade 3 of 3. in lymphovascular invasion is indentified.
Both have poorly fifferentiated invasive dutal carcimona with minimal lumen formation, intermediate to high nuclear grade, and numberous mitotic figures (17/10 hpf in one and 32/l0hpf in other. also in 2, focal myxocartilaginous matrix production consistent with a metaplastic carcinoma.
two tumor appreared to be seperated by a narrow segment of benign breast tissue favoring two seperate tumors. however, the two do have a similar histologic appearance and possibilty that this represents a bilobed tumor cannot be entirely excluded.  if bilobed: 2 CM and 2.7. Matrix production in smallest tumor.
Is there a average time span to live with this type of cancer.
Thanks for any information.   Sarah Bier
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Dear Sarah Bier:  In a situation where there is more than one tumor, the largest of the tumors is considered for staging purposes.  The "p" stands for pathologic staging (that means it was measured by pathology after removal)  T1C indicates that the tumor is more than one centimeter but not more than 2 cm in greatest dimension.  pN0 means that there are no regional lymph nodes involved with cancer.  pMX means that metastasis has not been assessed.  Based on this information, this represents a stage 1 breast cancer (with a notation of multiple primaries in one breast).  In this situation, the goal of therapy is cure. Treatment to improve chances of cure generally includes some combination of surgery, radiation therapy and chemotherapy. Most metaplastic carcinomas are hormone receptor negative, but the tumor should be checked for ER and PR as well as for Her2neu so that the oncologist can make appropriate postoperative treatment recommendations.
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