My aunt was diagnosed as breast cancer and had it operated last November. It is 1.0*2.5cm,infiltration type,no lymphonode matestasis.ER and PR are positive,CerbB2 is positive. Is Tamoxifen still useful for her? She is receiving chemotherapy with Oxaliplatin and Vinorelbine. Do you think it is proper for her?
Thanks for your help.
Dear sea-gull, According to the current data available the recommendation for tamoxifen is that women with invasive breast cancer who have positive lymph nodes or tumors greater than 1cm with positive hormone receptors should receive adjuvant tamoxifen for a period of 5years. The chemotherapy drugs you have noted are not standard of care for adjuvant therapy (therapy given after surgery to try to prevent or minimize the growth of microscopic deposits of tumor cells that might grow into a recurrent tumor). Perhaps your aunt is participating in a clinical research trial or there is information not noted here, that would clarify this particular recommendation for chemotherapy.
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