Tamoxifen effects on blood glucose levels

[AZGolfer57]

Are weight loss and drops in blood glucose levels side effects of tamoxifen?  I had a lumpectomy for DCIS one year ago and have been on tamoxifen for 10 1/2 months.  I started taking the tamoxifen in the evenings; however, I found that I wasn't sleeping well, so I began taking it in the mornings.  I find that if I do not take it with my breakfast or immediately after, my blood gluclose levels drop sharply.  In addition, since March of this year I have lost a total of 12 pounds, 8 in the last 5 weeks.  I am 5'4" and now weigh 105.6 clothed.  

[Cleveland Clinic]

Dear  AZGolfer57:  Weight loss has been reported uncommonly in women taking tamoxifen.  Hypoglycemia, however, is not a documented side effect of tamoxifen.  

[AZGolfer57]

I don't have Diabetes, although I have had hypoglycemia for years.  I am waiting for results of some blood tests to see what they may show.  

[katarina777]

Oh, and PS: I also had to lower my thyroid replacement dose as a result of taking Tamoxifen.

[katarina777]

Do you have Diabetes? Your comment is of interest to me, since, now that you mention it, I am wondering if my own blood glucose levels don't also fall as a result of taking the Tamoxifen at night. (in my case)

I hear most people complain of weight gain from the medication. I also, though, lost some weight.