Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum.  ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
Breast Cancer  (Expert Forum)
 | 
Understanding pathology report
Answered by
Cleveland - OH
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.

Understanding pathology report

by Pandora815, May 24, 2007 12:00AM
I had a stereotactical biopsy 4/07 which showed atypical ductal hyperplasia, sclerosing adenosis and apocrine metaplasia.  I then had a needle localization and excision.  Final patholgy report reads:  Proliferative fibrocystic changes including sclerosing adenosis, apocrine metaplasia, focal lobular hyperplasia and microcyst formation.  No evidence of malignancy.  My surgeon has referred me to a medical oncologist.  I am just wondering what the "standard" course of treatment is for this diagnosis.  I am 40 years old.  My husband and I are contemplating having more children(we miscarried in 2/07).  We are wondering what effect this diagnosis would have on a future pregnancy.  Thank you for your time.

by Cleveland Clinic, May 24, 2007 12:00AM
Dear Pandora815:  Your pathology report is benign.  The only factor that may lead to further discussion is the atypical ductal hyperplasia, which is a known risk factor for breast cancer.  A discussion with a medical oncologist may help determine your personal risk and determine the options for prevention/surveillance moving forward.  Having children at your age may increase your risk but this is a discussion to have with your physician.  
Member Comments (5)

by 555boston, May 25, 2007 12:00AM
Proliferative changes that you describe are know risk factors for future breast cancer. Risk depends on other factors too, like family history, age of menarche, age of first live birth etc etc. Your oncologisyt will be able to give you a better idea about your individual risk. Tamoxifen and Raloxifine are known to reduce risk of breast cancer, but may not be a good option if u are planning a pregnancy. Usually, people have to take these for around 5 years.

by sumanb, May 28, 2007 12:00AM
To: Side effects of Hormone treatment
I am ER/PR, pos node negative, her2 negative with a very low onc score. I am still undecided on Chemo. It is given that I will be on Armidex or some type of hormone treatment for 5 years regardelss of my choice with respect to chemo. There are side effect with Hormone treatment also such as weight gain, extreme dryness, thinning or hair etc. Can one skip hormone treatment by going through Chemo and removing the other breast to elimiate regional recurrence?

by 555boston, May 28, 2007 12:00AM
If your pathology spp did not show invasive malignancy (as per the report you posted) then you dont need chemo. If this was recommended to you, avoid that physician in the future. In addition, arimidex is not given to premenopausal women (i assume you to be one as you mentioned some thing about wanting a pregnency), and it is usually not given to women with precancerous lesions, like you describe.
If these options were given to you by an oncologist, he should have his lisence revoked.

by 555boston, May 28, 2007 12:00AM
Please ignore above comment, i thought ths was follow up question on the same started by Pandora.
Related discussions
Continue discussion
RSS Expert Activity
Prevention Gains Momentum: Your Gui... 
Nov 29 by Lee Kirksey, MD
What You Don't Know About Breathing...
Nov 24 by Steven Y Park, MD
Thanksgiving
Nov 23 by Thomas Dock, Vet. Technician