BREAST CANCER EXPERT FORUM
What exactly do these biopsy results mean?

What exactly do these biopsy results mean?

Specimen A and B show poorly differentiated invasiveGestational trophoblastic disease
Invasive
Minimally invasive heart surgery
Noninvasive
Noninvasive test
Squamous cell carcinoma - invasive ductal adenocarcinoma.  Multiple foci of high grade ducal carcinoma in situ with comedo type necrosis are noted.  P63 IHC stain supports diagnosis.  No definate lymphvascular invasion is seen on D2-40 IHC stain.  Microcalcifications are identified.

Diagnosis:  A and B say "Breast, left stereotactic bipsy:  InvasiveGestational trophoblastic disease
Invasive
Minimally invasive heart surgery
Noninvasive
Noninvasive test
Squamous cell carcinoma - invasive poorly differentiated ductal adenocarcinoma.  High grade ductal carcinoma in situ with comedo type necrosis.

I have an appt. Mon with breast surgeron.  What exactly does this mean for me?  What kind of cancer is this?  I would imagine I would find out staging when I have surgery.  Radiation therapy?  Chemo?  Lumpectomy?  What might be next?  Surgery?

40 years old on 10/31/09.  Thanks.
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242527_tn?1292452740
Dear spankyandrex:  This breast biopsy shows breast cancer.  In addition, there are other pathologic abnormalities that may require additional evaluation and testing, possibly with a gynecologist.  Depending on the situation, it may also be worth having the pathology reviewed at a second institution.  Hopefully, your doctor will be able to clarify much of this in the context of your situation.
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OH MY, I copied and pasted some stuff over that was not supposed to be!  Please let me repost it.  How embarressed I am.  Thanks.
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Ok, this is right now and my apologies.  Thank you so much!

Specimen A and B show poorly differentiated invasive ductal adenocarcinoma.  Multiple foci of high grade ducal carcinoma in situ with comedo type necrosis are noted.  P63 IHC stain supports diagnosis.  No definate lymphvascular invasion is seen on D2-40 IHC stain.  Microcalcifications are identified.

Diagnosis:  A and B say "Breast, left stereotactic bipsy:  Invasive poorly differentiated ductal adenocarcinoma.  High grade ductal carcinoma in situ with comedo type necrosis.

I have an appt. Mon with breast surgeron.  What exactly does this mean for me?  Radiation?  Chemo?  Lumpectomy?  What might be next?  Surgery?

40 years old on 10/31/09.  Thanks.
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242527_tn?1292452740
Dear spankyandrex:  This does make more sense.  Next steps, however, cannot be determined by a pathology report alone.  These decisions are based on the size of the invasive component, the extent of the DCIS, ER/PR Status, HER2 neu status and other factors that are not included on this report.  Your doctor will be far better able to answer these questions as they pertain specifically to you.
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